Endocrine Abstracts

Introduction: Gestational diabetes mellitus (GDM) is a condition that occurs during pregnancy when the body cannot produce enough insulin to handle the effects of a growing baby and changing hormone levels. Numerous studies reported that an increased risk of GDM among women who are overweight or obese compared with lean or normal-weight women.

Methods/design: The purpose of this study is to compare anthropometric and biochemical parameters in postmenopausal women with a history of GDM and controls. Subjects were 28 overweight/obese, postmenopausal and sedentary women who had a history of GDM and 27 postmenopausal without a history of GDM as healthy postmenopausal controls.

Results and conclusion: We observed significantly higher ALB, Protprandial insulin, ANTIT and GGT levels in patient with gestational diabetes while decreased FSH, LH and Thyroglobulin levels. We could not find any differences in fasting glucose, BMI, WHR, TSH and ALT levels. This study supported that GDM is a predisposing factor for DM after menopause.