ECE2014 Poster Presentations Diabetes (epidemiology, pathophysiology) (63 abstracts)
Pregnancy outcomes in women with gestational diabetes
Bojan Vuković 1, , Milena Mitrović 3, , Djordje Popović 3, , Dragana Tomić-Naglić 3, , Jovanka Novaković-Paro 3, , Olivera Rankov 4, , Radoslav Pejin 3, , Edita Stokić 3, & Branka Kovačev-Zavišić 3,
1Clinical centre of Vojvodina, Emregency centre, Novi Sad, Serbia; 2Medical Faculty University of Novi Sad, Novi Sad, Serbia; 3Clinical centre of Vojvodina, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Novi Sad, Serbia; 4Clinical Centre of Vojvodina, Clinic for Obstetrics and gynecology, Novi Sad, Serbia.
Introduction: Although diagnostics and therapy are much improved over the years, women with gestational diabetes still have more adverse course and outcome of pregnancy than healthy women. Their pregnancies are more often complicated with the different forms of maternal and fetal morbidity. Our study investigates all cause early neonatal morbidity (neonatal jaundice, neonatal hypoglycemia, fetal distress syndrome and other) and newborns maturity and vitality in the groups of delivered gestational diabetes and healthy women.
Methods/design: Retrospective study included 96 delivered gestational diabetes women and 106 delivered healthy women. We analyzed age of delivered women, incidence of caesarian section, gestational week at the time of delivery, Apgar score in first and 5th min, birth weight and length and incidence of all cause early neonatal morbidity in two groups. In statistical analysis we used mean values, proportions, t-test and test of proportions.
Results: There were no significant differences in age of women and incidence of caesarian section. Women with gestational diabetes gave birth at earlier gestational week (P=0.0455). Both Apgar scores were lower in newborns of delivered gestational diabetes women (P=0.0182; P=0.0012). Birth length was greater in newborns of delivered gestational diabetes women (P=0.0309) and difference in birth weight was on border of statistical significance (P=0.0561). All cause early neonatal morbidity had higher incidence in newborns of gestational diabetes women (P=0.0014).
Conclusion: Current guidelines for the screening on gestational diabetes during the pregnancy enabled timely diagnosis and adequate treatment of this condition. This allowed gestational diabetes women to carry their pregnancy almost similar as healthy women. However, offspring of gestational women still tends to be macrosomic, so these women deliver at earlier gestational week than healthy women. Their newborns earn lower Apgar score and the incidence of all cause early neonatal morbidity in this group is greater comparing to delivered healthy women.
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Endocrine Abstracts
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