Endocrine Abstracts

The work was initiated to assess and monitoring of basic epidemiological parameters of type 1 DM among children in the course of the 2000–2007 National Register. Epidemiological data was studied on the basis of annual reports from 13 regional endocrinological dispensaries and Tashkent endocrinological dispensary as well as on the basis of register cards filled up by local endocrinologists–pediatricians. In Uzbekistan within the period from 2000 to 2007 type 1 DM prevalence increased from 7.5 to 11.0 per 100 000 of pediatric population. The highest prevalence was observed in Tashkent (17.7), in Bukhara region (16.6) and in Tashkent region (14.5), the lowest one in Kashkadarya region (7.1) and in Surkhandarya region (7.7). Pediatric incidence in 2007 as compared with 2000 reduced from 2.7 to 2.1 per 100 000 of pediatric population. Analysis of pediatric incidence in 2007 revealed the highest one in Tashkent (4.6) and in Syrdarya region (2.7), the lowest being found in Navoi region (0.9). As to age distribution children aged from 10 to 14 comprised the largest group (66.6%), the smallest including children from 0 to 4 years (5.0%), 28.3% accounting for patients aged from 5 to 9. As to the disease duration children with type 1 DM duration less than 5 years comprised the largest group (70.9%), in the smallest one (2.1%) including patients with 10-year DM duration. As a whole, in Uzbekistan within the period of the Register fulfillment mortality level reduced from 0.1 to 0.03 per 100,000 of pediatric population. In 2007 mortality cases were registered in Kashkadarya region (0.1), Navoi region (0.4) and Samarkand region (0.09 per 100,000 of pediatric population. As a whole in Uzbekistan mortality reduction in children with type 1 DM within the period from 1998 to 2007 was 99%. Within the period of the National Register reduction in mortality paralleling alterations in structure of death cause and increase of survival can be noted to suggest perfect choice of strategy and tactics of the Register fulfillment.