Endocrine Abstracts

Among diseases with impaired carbohydrate metabolism, DM type 2 takes first place. And one of the main complications of this non-communicable disease is cardiovascular lesions. Our joint Ukraine-Poland research to actively detect DM type 2 took place during the Euro-2012, where we examined Hb1Ac in different ages of the population in both countries. In Ukraine the study involved 1564 individuals who where tested although they considered themselves free of DM. Their ages varied from 18 to 90 years with the following percentage scheme: 20% - up to 45 years (male-44%); 37% - 46–59 years (male-40%); 31% - 60–74 years (male-18%) and 12% - over 75 years (male-36%). We were directed by the following criteria: Hb1Ac level up to 6% - normal; Hb1Ac level 6.1 to 6.4% - belong to the prediabetic group, Hb1Ac level more than 6.5% - were considered potential patients with DM type 2. The study of people with excessive Hb1Ac content showed the following figures. Male: age group 45 years - Hb1Ac - 6.1–6.4%–50%, Hb1Ac - more than 6.5% –50%; age group 46–59 years was 30 and 70% respectively; age group 60–74 years - 18 and 82%; age group 75–90 years - 50 and 50%. Female: age group of 45 - 50 and 50%; age group 46–59 - 40% and 60%; age group 60–74 years - 36 and 74%; age group 75–90 years - 14% and 86%. The survey results show that carbohydrate metabolism disorders with the Hb1Ac parameters, typical to DM type 2, increase in accordance with age reaching the maximum at 60–74 years in male group and 75–90 years in female group. In this cohort study of tested people - 72% were healthy subjects with Hb1Ac level less than 6%. In 12% - Hb1Ac level within 6.1–6.4%, these people require careful monitoring and preventive measures for DM type 2. In 16% - Hb1Ac level was higher than 6.5% reaching sometimes 8%, this group requires additional studies for revealing DM type 2. Active treatment of these patients would help to serve as secondary prevention of cardiovascular lesions. In this study the Hb1Ac more than 6.5% was found in 16% of tested people. Number of patients with Hb1Ac more than 6.5% increases with age and is highest in males of the age group 60–74 years and females of the age group 75–90 years. Considering the fact that not all invited people agreed to be tested, draws attention that Ukrainians is not very enthusiastic towards necessary research to actively detect DM.