ECE2014 Poster Presentations Cardiovascular Endocrinology & Lipid Metabolism (41 abstracts)
Identification of 4 statin benefit groups according to NHLBI ATP IV criteria among Venezuelan women: EEM–lipid study
Wilfredo Guanipa-Sierra 1 , Martha Sánchez-Zambrano 2 , Josefina Feijoó-Iglesias 2 , Rita Pizzi-La Veglia 3 , Ingrid Márquez 2 , Félix Sánchez 4 , Adalberto Lugo 5 , Egleé Castillo 6 , Luis Díaz 7 & Auris Flores 8
1‘Van Grieken’ University Hospital, Coro, Falcón, Venezuela; 2‘Dr. Domingo Luciani’ Hospital, Caracas, D.C., Venezuela; 3Clinic Universitary Hospital, Caracas, D.C., Venezuela; 4‘Paraguaná’ Polyclinic, Punto Fijo, Falcón, Venezuela; 5CESCARDIM, Maracaibo, Zulia, Venezuela; 6‘La Viña’ Polyclinic Center, Valencia, Carabobo, Venezuela; 7‘Santa Rosa’ Clinic Center, Cumaná, Sucre, Venezuela; 8ASCARDIO, Barquisimeto, Lara, Venezuela.
The 2013 guideline (NHLBI ATP IV) on the treatment of blood cholesterol in adults was recently published. It focuses on identification of 4 Statin Benefit Groups (4SBG), in which the potential for Atherosclerotic Cardiovascular Disease (ASCVD) risk reduction benefit clearly exceeds the potential for adverse effects.
Objective: To estimate the prevalence of 4SBG among Venezuelan women and to determine its association with hypertension, BMI, waist circumference (WC), fasting blood glucose, age, obesity, reproductive history, socioeconomic status, and lifestyle.
Methods: In this cross-sectional study, a sample of 527 women (40–75 years old) was selected in gynecology clinics from 24 provinces of Venezuela. The levels of blood pressure, serum glucose, Col-T, HDLc, LDLc, and TG were measured for all them. 4SBG was defined according to ATP IV: i) clinical ASCVD; ii) LDLc ≥190 mg/dl; iii) diabetes and LDLc 70–189 mg/dl; iv) neither ASCVD nor diabetes, LDLc 70–189 mg/dl, estimated 10-year ASCVD risk ≥7.5% (by Pooled Cohort Equations).
Results: The prevalence (95% CI) of 4SBG, namely A, B, C, and D were 2.7 (1.2–4.0), 8.3 (6.0–10.7), 19.3 (16.5–22.6), and 8.0% (5.7–10.2) respectively. Overall, 61.5% (58.9–64.1) of women did not belong to 4SBG. WC was higher in A and C groups. Prevalences of HTA and obesity were higher in 4SBG than in non 4SBG women (P<0.001). The prevalence of 4SBG women increased steadily in line with age (P<0.001). Interestingly, the prevalence was 100% in the 70-year-old age or older Group.
Conclusions: EEM-Lipid Study data indicate that nearly 40% of the Venezuelan women (40–75 years old) would require the use of statins as recommended by NHLBI ATP IV. Furthermore, for all women over age 70 would be indicated using it. Therefore, effective public health education and urgent precautions are needed.
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more