ECE2014 Poster Presentations Cardiovascular Endocrinology & Lipid Metabolism (41 abstracts)
Adherence to treatment in hypertension and diabetes
Maryia Rusalenko 1 , Aleks Korotaev 1 , Nataliya Shilova 1 , Tatyana Mokhort 2 & Aleksandr Rozhko 1
1The Republican Research Center for Radiation Medicine and Human Ecology, Gomel, Belarus; 21Belarusian State Medical University, Minsk, Belarus.
Objective: To study the effectiveness of therapy and the role of adherence to treatment in patients with DM and AH.
Methods: A 75 patients studied with Moriski-Green test. Psycho-correctional work has been carried out with 37 people (Group 1) in order to increase motivation for treatment, and the work has not been carried out with 38 people (Group 2). The treatment effect has been evaluated after 3 months according the results of sBP and dBP dynamics and 24 h blood pressure monitoring.
Results: Out of 75 patients, 65% appear to be nonadherent to treatment. According to the results of initial examination the data of patients from the groups have no difference. The reduction of sBP, dBP has been reported in both groups after 3 months. According to the results of 24 h BPM, the normalization of average daily and night numbers has been set, as well as sBP and dBP in both groups; and only in the one group there has been noticed the reduction of sBP variability at night, daily index of sBP and dBP, rate of morning sBP and dBP increase, which are high risk indicators of cardiovascular events.
| Before treatment | After treatment | |||||
| Indicator (mmHg) | Group 1 | Group 2 | Group 1 | Group 2 | P1 | P2 |
| sBP | 165.6±17.9 | 168.6±20.5 | 130.0±9.8 | 127.5±10.5 | <0.001 | <0.001 |
| dBP | 102.8±11.1 | 113.7±9.6 | 80.0±9.1 | 69.7±17.5 | <0.001 | <0.001 |
| Average sBPd | 154.3±9.3 | 156.7±12.2 | 120.3±7.5 | 126.7±10.0 | 0.002 | 0.001 |
| Average sBPn | 138.8±8.7 | 140.1±8.9 | 111.4±7.3 | 112.6±7.1 | 0.001 | <0.001 |
| Average sBPd | 94.8±7.7 | 92.2±10.1 | 74.4±5.6 | 71.4±9.3 | 0.003 | 0.002 |
| Average sBPn | 88.2±6.2 | 86.9±11.0 | 66.7±4.6 | 71.4±9.3 | 0.005 | 0.016 |
| Var. sBPd | 13.8±3.9 | 13.3±3.2 | 13.4±3.2 | 13.5±3.3 | 0.462 | 0.483 |
| Var. sBPn | 13.0±2.1 | 12.6±3.0 | 11.6±1.8 | 12.0±2.9 | 0.024 | 0.083 |
Conclusion: Psycho-correctional training improves adherence of patients to treatment, which is accompanied by positive dynamics of 24 h BPM indicators.
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Endocrine Abstracts
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