ECE2014 Poster Presentations Calcium and Vitamin D metabolism (68 abstracts)
Vitamin D deficiency in Russian pregnant women and risk for gestational diabetes
Polina Popova 1, , Alexandra Dronova 1 , Elza Sadikova 1 , Mary Parkkinen 1 , Maria Bolshakova 1 & Elena Grineva 1,
1Almazov Federal Medical Research Centre, Saint-Petersburg, Russia; 2The First Pavlov St Petersburg State Medical University, Saint-Petersburg, Russia.
Introduction: Some, but not all, previously published studies suggest that low vitamin D status maybe associated with increased risk of gestational diabetes (GDM). We examined the association of plasma plasma 25-hydroxyvitamin D (25(OH)D) concentration with GDM risk and neonatal macrosomia.
Methods: 143 women were recruited before 15 weeks of gestation and were followed-up until delivery. Maternal plasma 25(OH)D concentrations were measured at 8–14 weeks of gestation. Two-hour 75 g oral glucose tolerance test (OGTT) was performed between 24 and 28 weeks of gestation. GDM was diagnosed according to IADPSG criteria. The neonatal anthropometry was also measured.
Results: GDM was revealed in 19 women (13.3%). Mean 25(OH)D levels were 21.8±8.5 and 21.9±9.2 ng/ml (P=0.984) and the prevalence rates for vitamin D deficiency (25(OH)D levels <20 ng/ml) were 52.6 and 45.2% (P=0.625) in women who developed GDM and in women without GDM respectively. Maternal 25(OH)D was unrelated to the results of OGTT or neonatal anthropometry. Only 19% of women reported the use of vitamin D supplements before the first prenatal visit and 57.4% of women had been taking it by the time of OGTT performance
Conclusion: Early pregnancy vitamin D deficiency was very common in the studied population of pregnant women. There was no association between maternal 25(OH)D and gestational diabetes.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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