ECE2014 Poster Presentations Calcium and Vitamin D metabolism (68 abstracts)
Correlation between 25-OH vitamin D3 and TSH concentration in population over 65: preliminary report
Joanna Przybylska- Just 1 , Anna Bronczyk-Puzon 2, , Justyna Nowak 3, , Aneta Koszowska 3, , Anna Dittfeld 4 , Pawel Jagielski 5 & Barbara Zubelewicz-Szkodzinska 6,
1Department of Geriatrics, County Hospital, Piekary Slaskie, Poland; 2Doctoral Study in the School of Health Care Medical University of Silesia, Katowice, Poland; 3Doctoral Study in the School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia, Katowice, Poland; 4Doctoral Study in the School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, Katowice, Poland, 5Faculcy of Clinical Biochemistry, Institute of Genetic Diagnostics and Nutrigenomics, Collegium Medicum of Jagiellonian University, Krakow, Poland; 6Department of Endocrinology, County Hospital, Piekary Slaskie, Poland; 7Department of Nutrition-Associated Disease Prevention, Faculty of Public Health Medical University of Silesia, Bytom, Poland.
Introduction: Active metabolites of vitamin D have pleiotropic influence on whole body.
Aim: The aim of the study was evaluation of the correlation between vitamin D3 and TSH values in population over 65.
Materials and methods: 94 patients admitted to diagnosis on Geriatric Department entered the study. People with age above 65 were included to research and divided on two groups according to sex. The material samples were obtained from patients in the morning during routine sampling. The concentration of 25-OH vitamin D were determined by ELISA. The obtained data were statistically analyzed using STATISTICA. α=0.05.
Results: The examined group consist of 26 men (27.66%) and 68 women (72.34%). The average age of whole group was 77.55±6.76 years. The average age of a group of men was 75.96±6.51 years and groups of women 78.16±6.80 years (P=0.1460). The average concentration of 25-OH vitamin D3 in the study population was 14.18±5.60 ng/ml in men and 15.85±6.36 ng/ml in women 13.55±5.19 ng/ml. The average value of TSH in the study group was 1.82±1.28 μIU/ml in men and 1.41±0.64 μIU/ml in the group of women 1.98±1.43 μIU/ml. There were no statistical significance observed in women group in relation to 25-OH vitamin D3 and TSH concentration and between TSH concentration and 25-OH vitamin D3 in the whole group. There was observed statistically significance negative correlation between 25-OH vitamin D3 and TSH in analyzed group of men (R=−0.43; P=0.0329).
Conslusions: Current studies showed negative correlation between 25-OH vitamin D3 and TSH concentration in group of men while it is not observe of women. The future researches are necessary in order to obtain accurate results.
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Endocrine Abstracts
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