ECE2014 Poster Presentations Bone and Osteoporosis (36 abstracts)
Bone mineral density in Iranian patients: effects of age, sex, and BMI
Mehrdad Aghaei 1 , Hamidreza Bazrafshan 1, , Mostafa Qorbani 2 , Mahdieh Shojaa 3 , Hossien Shadpour Dashti 1 , Payam Sarmadi 1 & Roya Safari 4
1Joint,bone and Connective Tissue Research Center, Golestan University of Medical Sciences, Gorgan, Iran; 2Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran; 3Osteoporosis Research Center, Tehran University of Medical Sciences, Tehran, Iran; 4Department of Internal Medicine, Tehran University of Medical Sciences, Tehran, Iran; 5Neuroendocrinology Group, Max Planck Institute of Psychiatry, Munich, Germany.
Introduction: Osteoporosis is a multifactorial skeletal disease that is characterized by reduced bone mineral density (BMD). BMD values depend on several factors such as age, sex and age at menopause. The purpose of this study was to determine the prevalence and changes in BMD in Iranian patients.
Methods: Three hundred patients were selected through random sampling technique in 2009. BMD was assessed by Norland machine at the lumbar and femoral neck. Weight and height were measured through standard methods. A thorough history was taken from each patient. The data was analyzed using SPSS software version 13.0. P values < 0.05 were considered statistically significant.
Results: From among the 300 studied patients, 86.6% were female. Their mean age was 52.7 years. Their average BMI was 28.14 kg/m2. Mean T-score at lumbar spine and femoral neck was −1.07±1.19 and −1.75±1.33 respectively. Mean BMD value at lumbar spine and femoral neck was 0.92±0.19 and 0.77±0.16 respectively. The prevalence of osteoporosis at lumbar spine and femoral neck was 33.7% and 16.7 respectively. There was a significant correlation between age, BMI and BMD values (P value <0.01). Correlation between gender and BMD value at the lumbar spine and femoral neck was not significant.
Conclusion: This study shows that ageing and low BMI are risk factors associated with bone loss. It is recommended to measure BMD and implement prevention programs for high-risk people.
Keywords:: bone mineral density, BMI, age, gender
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Endocrine Abstracts
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