ea0035pl1 | Genes, environment and endocrine disease | ECE2014
Ordovas Jose M
Current knowledge supports the notion that the onset and progression of endocrine and age-related diseases depend on an individuals metabolic flexibility. With respect to cardiometabolic diseases, especially in older persons, several factors act in concert and converge to challenge metabolic flexibility. These include an inadequate diet, insufficient physical activity, chronodisruption, decreased metabolic reserve, altered gut microbiome, and reduced immune system capaci...