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Endocrine Abstracts

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16th European Congress of Endocrinology

Meet the Expert Sessions

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ea0035mte1 | (1) | ECE2014

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ea0035mte2 | (1) | ECE2014

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ea0035mte3 | (1) | ECE2014

Premature ovarian insufficiency

Christin-Maitre S

Premature ovarian failure or primary ovarian insufficiency (POI) is characterized by amenorrhea occurring before the age of 40-year-old, with elevated gonadotropins (FSH >20 mIU/ml). It affects 1–2% of women. So far, in more than 75% of cases, its etiology remains unknown.The obvious causes are chemotherapy, radiotherapy and ovarian surgery, mainly for bilateral ovarian endometriomas. Genetic causes of POI include rare diseases, such as blepharo...
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ea0035mte4 | (1) | ECE2014

The zebrafish, a teleost model recapitulating the mammalian molecular events during endocrine development and function

Tiso Natascia , Busolin Giorgia , Ek Olivier , Marelli Federica , Porazzi Patrizia , Vettori Andrea , Facchinello Nicola , Schiavone Marco , Casari Alessandro , Astone Matteo , Milanetto Martina , Moro Enrico , Campione Marina , Persani Luca , Argenton Francesco

In the last decades, the tropical teleost zebrafish (Danio rerio) has proved to be an excellent vertebrate system to model mammalian molecular events occurring during embryonic development, organ formation and adult physiology, either under normal or pathological conditions. Low costs and small dimensions, external fertilization and high fecundity, tissue transparency, rapid development, availability of mutant and transgenic lines, easy manipulability for gene perturb...
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ea0035mte5 | (1) | ECE2014

The Year in the Adrenals

Reincke Martin

In this session, the most recent publications related to the topic and published in 2013/2014 will be discussed and set into a clinical and problem-oriented context. In primary aldosteronism three Nature genetics papers have elucidated the genetic basis of aldosterone-producing adenomas. In addition, an important AVS expert consensus has been published (Hypertension 2014). Also, in 2014, a revised Endocrine Society Practice Guidline for primary aldosteronism is expected (JCEM...
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ea0035mte6 | (1) | ECE2014

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ea0035mte7 | (1) | ECE2014

Therapeutic dilemmas in NETs

Kudla Beata Kos

During recent years, there has been some increase in the incidence of gastroenteropancreatic neuroendocrine tumours (GEP–NETs). In spite of noticeable advances in development of contemporary diagnostics and therapeutics, neuroendocrine tumours still present many clinical challenges to every-day clinical practice.Therapeutic dilemmas will be presented as a case study including an example of a male patient JA, aged 68, diagnosed with hormone inactive ...
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ea0035mte8 | (1) | ECE2014

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ea0035mte9 | (1) | ECE2014

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ea0035mte10 | (1) | ECE2014

Pituitary disorders and osteoporosis

Bolanowski Marek

Different hormonal disorders can influence bone metabolism and cause secondary osteoporosis. In childhood, pituitary disorders hamper gaining of proper peak bone mass and skeletal size, later on in the adult life they can increase bone loss. The consequence of diminished bone strength is significant increase of fracture risk. Among pituitary disorders such effects are possible in patients with GH, prolactin, gonadotropins secretion disturbances, and GH and ACTH excess, while h...
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ea0035mte11 | (1) | ECE2014

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ea0035mte12 | (1) | ECE2014

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ea0035mte13 | (1) | ECE2014

Pituitary apoplexy: diagnosis and management

Wass John

Pituitary apoplexy is an uncommon emergency. It presents often with sudden thunder clap headaches and requires multidisciplinary team involvement. This includes an experienced neurosurgeon, endocrinologist, radiologist – the pituitary multidisciplinary team.Urgent treatment should be given often involving steroids (after a blood cortisol has been taken). Assessment includes neurological signs which if severe may merit urgent surgery.<p class="ab...
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ea0035mte14 | (1) | ECE2014

Real-time monitoring of GPCR signalling in living cells

Calebiro Davide

G-protein coupled receptors (GPCRs) constitute the largest family of receptors and mediated the effects of many hormones and neurotransmitters. Whereas GPCRs and their signalling cascades have been intensively studied at the molecular and, more recently, structural level, many important aspects of GPCR signalling remain elusive. A major reason for this resides in the limited spatial and temporal resolution of standard biochemical methods. To overcome these limitations, we and ...
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ea0035mte15 | (1) | ECE2014

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ea0035mte16 | (1) | ECE2014

Postmenopausal hyperandrogenism

Kaltsas Gregory , Markopoulos Marios

Menopause is a state of relative hyperandrogenism resulting from the abrupt fall of estrogen levels due to ovarian senescence and the steady decline of androgen levels with aging. Frank hyperandrogenism, characterized by hyperandrogenemia and clinical hyperandrogenism, in postmenopausal women is most commonly the result of functional causes of hyperandrogenism, which usually pre-exist menopause from early reproductive years, and are aggravated by the physiological changes of m...
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ea0035mte17 | (1) | ECE2014

FGF23 and phosphorus homeostasis: physiology and pathophysiology

Navarro-Gonzalez Juan

The great majority of the phosphorus in the body is found as phosphate (PO4). Phosphate is critical for the maintenance of bone and skeletal integrity, is a necessary component of important biomolecules, such as RNA and DNA, and is central to signal transduction and cell metabolism. The appropriate serum phosphate concentration is maintained based on the endocrine communication between the skeleton, the kidney, and the intestine. The classical view of phosphate regu...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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