Endocrine Abstracts

This study aimed at investigating the effect of high sucrose diet on male reproductive function and if Nigerian honey could exert a protective role. Twenty-four rats were randomly divided into four equal groups of six animals and given water (control); honey (H); high sucrose solution (30%w/v) (HSS); and both high sucrose solution (30%w/v) and honey (HSS+H). Each rat on honey received a daily dose of 10 ml honey/kg per 5 ml of distilled water. Food intake, body weight, organ weight, fasting blood glucose, LH, FSH, testosterone and sperm functions were assessed. This revealed that sperm motility (P<0.05) and count increased in the HSS+H and H-fed rats compared with HSS fed and control rats. Head and tail abnormalities sperm were also significantly reduced in the H fed rats (P<0.05). MDA level in the liver and not in the testes was significantly increased in the HSS fed rats compared with control while SOD activity was significantly increased in HSS+H rats compared with the HSS fed rats. The results indicate that sucrose feeding impact negatively on sperm function while Nigerian honey supplementation confers protective function on male reproduction.