Endocrine Abstracts

Type 2 diabetes with poor glycemic control is a predisposing factor for periodontitis (Salvi et al. 2000). In this cross sectional study, subjects with type 2 diabetes (n=232, mean age: 50.08±3.2 years) were recruited with informed and written consent. Fasting plasma glucose, serum lipid profile and HbA1c was analysed by standardised methods. A complete dental examination for pocket depth, clinical attachment level and periodontitis was performed for all subjects. Clinical data was analysed for statistical significance by Pearson’s correlation and linear regression models to determine the predictor variables that determine gingival index in type 2 diabetic subjects with periodontitis (n=108) and without periodontitis (n=123). In T2DM subjects with periodontitis, the mean HbA1c (7.74%), mean pocket depth (5.79), gingival index (2.86) was comparatively higher than subjects without periodontitis. A positive correlation was observed between gingival index and HbA1C, HDL cholesterol (HDL-C) clinical attachment level (P=0.001) and BMI (P=0.05). The predictive variables for gingival index were pocket depth (P=0.000), HbA1c (P=0.000) and total body weight (P=0.000) with a regression coefficient (r²) of 0.67. The observations of the present study infer that HbA1c, HDL, BMI and pocket depth are predictive clinical variables for periodontitis in type 2 diabetes subjects with elevated HbA1c values.