Endocrine Abstracts

Contents

• Plenary Lecturers’ Biographical Notes
• • SfE Dale Medal Lecture 2013
  • • Abstract unavailable

      ea0034pl1
    • Society for Endocrinology Dale Medal Lecture 2013

      ea0034pl1biog
  • SfE Dale Medal Lecture 2014
  • • Nuclear receptor coactivators: master genes for physiology and pathology

      ea0034pl2
    • Society for Endocrinology Dale Medal Lecture 2014

      ea0034pl2biog
  • Clinical Endocrinology Trust Visiting Professor Lecture
  • • Adrenocortical tumours: from bench to bedside and back

      ea0034pl3
  • SfE European Medal Lecture
  • • Mechanisms of thyroid hormone resistance

      ea0034pl4
  • SfE Transatlantic Medal Lecture
  • • Transcriptional coordination of circadian and metabolic physiology

      ea0034pl5
    • SfE Transatlantic Medal Lecture

      ea0034pl5biog
  • BTA Pitt-Rivers lecture
  • • Disorders of thyroid hormone action: insights from human genetics

      ea0034pl6
    • British Thyroid Association Pitt-Rivers Lecture

      ea0034pl6biog
  • SfE Medal Lecture
  • • The clock in the pituitary gland: timing annual cycles

      ea0034pl7
  • Clinical Endocrinology Trust Lecture
  • • Understanding glucocorticoid action, and the role of the glucocorticoid receptor

      ea0034pl8
    • Clinical Endocrinology Trust Lecture

      ea0034pl8biog
  • SfE Hoffenberg International Medal Lecture
  • • Male fertility regulation: achievements and frustrations

      ea0034pl9
    • SfE Hoffenberg International Medal Lecture

      ea0034pl9biog
• Society for Endocinology Journal Awards
• • Society for Endocrinology Journal Award ‐ Journal of Endocrinology
  • • Mice deficient in PAPP-A show resistance to the development of diabetic nephropathy

      ea0034ja1
  • Society for Endocrinology Journal Award ‐ Journal of Molecular Endocrinology
  • • Thyroid-specific inactivation of KIF3A alters the TSH signaling pathway and leads to hypothyroidism

      ea0034ja2
  • Society for Endocrinology Journal Award ‐ Endocrine-Related Cancer
  • • Highly prevalent TERT promoter mutations in aggressive thyroid cancers

      ea0034ja3
  • Society for Endocrinology Journal Award ‐ Clinical Endocrinology
  • • What predicts adverse outcomes in untreated primary hyperparathyroidism? The Parathyroid Epidemiology and Audit Research Study (PEARS)

      ea0034ja4
  • Society for Endocrinology Journal Award ‐ Endocrine Connections
  • • PKA regulatory subunit R2B is required for murine and human adipocyte differentiation

      ea0034ja5
• Symposia
• • GNRH biology ‐ from pulses to longevity (Supported by Journal of Molecular Endocrinology)
  • • Systems approaches to understanding GnRH signalling

      ea0034s1.1
    • Abstract unavailable

      ea0034s1.2
    • GnRH and inflammatory signalling in the ageing hypothalamus

      ea0034s1.3
  • The upside of glucocorticoids in metabolism (Supported by Journal of Endocrinology)
  • • Insulin sensitization of adipose tissue by glucocorticoids

      ea0034s2.1
    • Maintaining the anti-inflammatory action of GC without the metabolic side effects

      ea0034s2.2
    • A hair 'o' the dog that bit you? Elevated pancreatic [beta] cell glucocorticoid reactivation protects against [beta] cell failure

      ea0034s2.3
  • Emerging Clinical importance of iodine (Supported by Endocrine-Related Cancer)
  • • Inadequate iodine status in UK pregnant women adversely affects cognitive outcomes in their children: results from the Avon Longitudinal Study of Parents and Children (ALSPAC)

      ea0034s3.1
    • Regulation of NIS function in thyroid and breast cancer

      ea0034s3.2
    • Use of radioiodine in the imaging and therapy of non-thyroidal tumors

      ea0034s3.3
  • Putting flesh on the bones
  • • Assessment of abnormalities of skeletal development

      ea0034s4.1
    • Osteogenesis imperfecta: management beyond childhood

      ea0034s4.2
    • Management of hypophosphatemic rickets

      ea0034s4.3
  • Endocrine consequences of major trauma
  • • The immune-endocrine mechanisms of trauma-induced sarcopenia

      ea0034s5.1
    • Pituitary sequelae of traumatic brain injury

      ea0034s5.2
    • Thyroid hormone economy during critical illness

      ea0034s5.3
  • Thyroid cell biology comes to your clinic (Supported by Journal of Molecular Endocrinology)
  • • Development of functional thyroid tissue from embryonic stem cells

      ea0034s6.1
    • Abstract unavailable

      ea0034s6.2
    • PBF signalling in thyroid tumourigenesis

      ea0034s6.3
  • Natriuretic peptides: so much more than salt and water
  • • Guanylyl cyclases in cardiomyopathy

      ea0034s7.1
    • Natriuretic peptides in pituitary development and function

      ea0034s7.2
    • C-type natriuretic peptide and cardiovascular disease

      ea0034s7.3
  • Chronic disease and growth
  • • Understanding GH action through the growth plate'

      ea0034s8.1
    • Targeting SOCS proteins to combat inflammation

      ea0034s8.2
    • Managing abnormalities of growth in chronic diseases

      ea0034s8.3
  • MEN1 ‐ from molecular pathology to therapies (Supported by Endocrine-Related Cancer)
  • • Current understanding and future perspectives in MEN1: the molecular pathology of the MEN1 gene and menin

      ea0034s9.1
    • Genetics, pathophysiology and translational models of MEN1

      ea0034s9.2
    • Abstract unavailable

      ea0034s9.3
  • Fat and bone ‐ old neighbours, new relationships? (Supported by Endocrine Connections)
  • • Fat and its influence on bone

      ea0034s10.1
    • Obesity and fractures: what is the relationship?

      ea0034s10.2
    • Energy deficiency, amenorrhea and the skeleton: challenges and therapies

      ea0034s10.3
  • Some like it hot ‐ new insights into brown adipose tissue
  • • Molecular regulation of brown and beige fat cell fate

      ea0034s11.1
    • The metabolic capacities of brown adipose tissue

      ea0034s11.2
    • How brown is human BAT?

      ea0034s11.3
  • Getting excited about sugar - the brain and blood glucose control (Supported by Endocrine Connections)
  • • Abstract unavailable

      ea0034s12.1
    • Vagal control of energy metabolism

      ea0034s12.2
    • Does glucagon need the brain for its effects on blood glucose?

      ea0034s12.3
• Clinical Management Workshops
• • Workshop 1 (Supported by Clinical Endocrinology) Management of complex obesity
  • • Have the new commissioning guidelines for bariatric surgery improved patient's pathways?

      ea0034cmw1.1
    • Medical management of severe obesity

      ea0034cmw1.2
    • Endocrine and metabolic complications post-bariatric surgery

      ea0034cmw1.3
  • Workshop 2 (Supported by Endocrinology, Diabetes & Metabolism Case Reports) How Do I Do It?
  • • Abstract unavailable

      ea0034cmw2.1
    • How and when do I initiate treatment for central hypothyroidism?

      ea0034cmw2.2
    • Abstract unavailable

      ea0034cmw2.3
    • How do I investigate and manage sweating

      ea0034cmw2.4
    • Abstract unavailable

      ea0034cmw2.5
    • How I do: hyponatraemia

      ea0034cmw2.6
    • Abstract unavailable

      ea0034cmw2.7
  • Workshop 3 (Supported by Clinical Endocrinology) Improving the care of young people in endocrinology
  • • Adolescent health care in the UK in 2014

      ea0034cmw3.1
    • Adrenal replacement in adolescents and young adults

      ea0034cmw3.2
    • Optimising bone health in adolescents and young adults

      ea0034cmw3.3
  • Workshop 4 (Supported by Endocrinology, Diabetes & Metabolism Case Reports) Cardiovascular risk in endocrine disease
  • • Cardiovascular risk in Turner's syndrome

      ea0034cmw4.1
    • Valvular disease in prolactinomas: weighing up the evidence

      ea0034cmw4.2
    • Cardiovascular risk in childhood cancer survivors

      ea0034cmw4.3
• Applied Physiology Workshop (Supported by <emphasis role="italic">Journal of Endocrinology</emphasis>)
• • A guide to the analysis of energy metabolism
  • • Assessing energy demand in living organisms: the influence of environmental temperature

      ea0034apw1.1
    • Lipid metabolism: from mice to men?

      ea0034apw1.2
    • Tracking lipid energy partitioning in human liver

      ea0034apw1.3
• Meet the Expert Sessions
• • (1)
  • • Abstract unavailable

      ea0034mte1
    • Vitamin D replacement: how much, how often and for whom?

      ea0034mte2
    • Abstract unavailable

      ea0034mte3
    • Abstract unavailable

      ea0034mte4
    • Abstract unavailable

      ea0034mte5
    • Abstract unavailable

      ea0034mte6
    • Who should the endocrinologist ask the ophthalmologist to review?

      ea0034mte7
    • Abstract unavailable

      ea0034mte8
    • Novel techniques to assess angiogenesis

      ea0034mte9
• Education Workshops
• • Teaching and learning in Endocrinology
  • • Endocrinologists as teachers: integrating teaching and practice in the real world

      ea0034ew1.1
    • Using technology to enhance your teaching in Endocrinology

      ea0034ew1.2
    • Assessment in Medicine and Endocrinology

      ea0034ew1.3
    • Interprofessional learning through and for multidisciplinary working

      ea0034ew1.4
  • Practical publishing advice
  • • Abstract unavailable

      ea0034ew2.1
    • Abstract unavailable

      ea0034ew2.2
    • Abstract unavailable

      ea0034ew2.3
    • Abstract unavailable

      ea0034ew2.4
    • Responding to reviewer comments

      ea0034ew2.5
    • The art of scientific writing

      ea0034ew2.6
    • Abstract unavailable

      ea0034ew2.7
• Nurse Session
• • Cushing's Syndrome
  • • Investigating and diagnosing Cushing's syndrome: not as straightforward as it seems?

      ea0034n1.1
    • The role of the Endocrine Nurse in the Management of patients with Cushing's syndrome

      ea0034n1.2
    • Why do cured? Cushing's patients need long-term follow-up?

      ea0034n1.3
    • Abstract unavailable

      ea0034n1.4
  • The journey of endocrine nursing research: from evidence based practice to independent research
  • • The journey of endocrine nursing research: from evidence based practice to independent research

      ea0034n2.1
    • How to audit and evaluate your own practice

      ea0034n2.2
    • The role of the endocrine nurse in clinical trials

      ea0034n2.3
    • Independent nursing research

      ea0034n2.4
• Young Endocrinologists Session
• • SfE Young Endocrinologists' prize lectures
  • • Sox2+ cells of the postnatal pituitary can differentiate into hormone-producing cells in vivo and have tumour-inducing potential

      ea0034yep1.1
    • Clinical effects of kisspeptin on reproductive hormone secretion, LH pulsatility and oocyte maturation

      ea0034yep1.2
  • Establishing successful collaborations
  • • Abstract unavailable

      ea0034ye1.1
    • How do I talk to a bioinformatician/mathematician/engineer?

      ea0034ye1.2
    • Abstract unavailable

      ea0034ye1.3
    • Biobanking: what is it, and how could it be beneficial to me?

      ea0034ye1.4
    • Peer-to-peer collaborations: importance of YE groups

      ea0034ye1.5
• Senior Endocrinologists Session
• • (1)
  • • How important is luck for major scientific discoveries?

      ea0034se1.1
    • 1776: revolution in liverpool: Matthew Dobson discovers hyperglycaemia

      ea0034se1.2
    • Macroprolactin, to seek or ignore: a trans-Atlantic division

      ea0034se1.3
    • The Foundling hospital

      ea0034se1.4
    • Steroid merchants of Edinburgh

      ea0034se1.5
    • Reproductive biology in the enlightenment: some contributions of the hunter brothers

      ea0034se1.6
• Oral Communications
• • Young Endocrinologists prize session
  • • The Thr92Ala substitution in deiodonase-2 is associated with increased odds of a sub-optimal IQ score in children with low-normal thyroid function

      ea0034oc1.1
    • Characterisation of adrenocortical progenitor cells: isolation of mesenchymal stem cell-like cell populations from human adrenal cortex

      ea0034oc1.2
    • Angiogenic factors sFlt1 and PlGF are novel determinants of newborn thyroid (dys)function: the Generation R Study

      ea0034oc1.3
    • Single molecule analysis of GPCR transactivation reveals oligomeric complexes that regulate signal sensitivity

      ea0034oc1.4
    • Kisspeptin: a novel physiological trigger for oocyte maturation in IVF treatment

      ea0034oc1.5
    • A loss-of-function mutation in the prolactin receptor causes familial hyperprolactinaemia

      ea0034oc1.6
  • Endocrine regulation of cell behaviour
  • • A novel modulator of cell invasion and metastasis

      ea0034oc2.1
    • Inhibition of human NET cell proliferation by a peptide identified through phage display screening

      ea0034oc2.2
    • A20 confers protection against TRAIL-induced apoptosis in the pancreatic [beta]-cell

      ea0034oc2.3
    • Influence of glucocorticoid receptor density on development and remodeling of the heart

      ea0034oc2.4
    • [beta]-cells require CFTR for glucose-induced insulin secretion

      ea0034oc2.5
    • A potential role for food-derived microRNAs in human placental development

      ea0034oc2.6
  • Steroids
  • • Lack of 11[beta]-hydroxysteroid dehydrogenase type 1 ameliorates the adverse features of Cushing's syndrome

      ea0034oc3.1
    • 5[alpha]-reductase is a regulator of glucocorticoid action and metabolic phenotype in human liver

      ea0034oc3.2
    • The 21-hydroxylase pseudogene may have a role in induction of tolerance to steroidogenic machinery

      ea0034oc3.3
    • Pre-receptor glucocorticoid metabolism across human ageing: the impact of gender and menopausal status

      ea0034oc3.4
    • Linking GWAS to gene function: CYP17A1 in hypertension

      ea0034oc3.5
    • Targeting of lysyl oxidase by steroids to reduce peritoneal fibrosis and scarring

      ea0034oc3.6
  • Thyroid and bone
  • • Adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 exert dominant-negative effects

      ea0034oc4.1
    • PHOSPHO1: roles beyond skeletal mineralisation

      ea0034oc4.2
    • TR[alpha] mutation causes a severe and thyroxine-resistant skeletal dysplasia

      ea0034oc4.3
    • Thyroid hormones stimulate osteoclastogenesis via TR[alpha]-dependent actions in osteoblasts

      ea0034oc4.4
    • A mutation in the 5'-UTR of GNA11 causes familial hypocalciuric hypercalcemia type 2 due to reduced translational efficiency

      ea0034oc4.5
    • An ENU-induced Tyr265Stop mutation in Polg2 is associated with renal calcification in RCALC2 mice

      ea0034oc4.6
  • Pituitary
  • • Increased frequency and earlier onset of pituitary tumours in mice deleted for a multiple endocrine neoplasia type 1 allele and null for prolyl hydroxylase domain protein 1 (Men1+/-/Phd1-/-)

      ea0034oc5.1
    • Implications of the upregulation of lysine specific demethylase 1 in the pathogenesis of pituitary adenomas

      ea0034oc5.2
    • The Wnt/[beta]-catenin effector Tcf3/TCF7L1 is required for normal hypothalamic-pituitary development and mutation in this gene are associated to congenital hypopituitarism

      ea0034oc5.3
    • GnRH pulse frequency-dependent regulation of ICER, a modulator of FSH[beta] transcription, is attenuated by MEKI/II blockade

      ea0034oc5.4
    • Spatio-temporal analysis of prolactin gene transcription dynamics reveals short range co-ordination of lactotroph transcription activity in pituitary tissue

      ea0034oc5.5
    • A GH antagonist fusion with GH binding protein is biologically active, shows delayed clearance and inhibits growth in a rabbit model

      ea0034oc5.6
  • Clinical
  • • Adverse outcome in glucocorticoid induced adrenal suppression; an analysis of short synacthen tests in 2782 patients

      ea0034oc6.1
    • Localising parathyroid adenomas: which imaging modality is best? Pre-operative localisation studies in patients with primary hyperparathyroidism: a large audit in a London tertiary centre

      ea0034oc6.2
    • Sirolimus therapy for a patient with segmental overgrowth due to a mosaic activating mutation in phosphatidylinositol-3-kinase

      ea0034oc6.3
    • Reduced cognitive performance and altered white matter microstructure in young insulin-resistant women with polycystic ovary syndrome

      ea0034oc6.4
    • Effectiveness of metyrapone in 195 patients with Cushing's syndrome

      ea0034oc6.5
    • 11C-methionine PET-CT co-registered with volume MRI: a novel adjunctive imaging modality to aid diagnosis and management in patients with pituitary adenomas

      ea0034oc6.6
• Poster Presentations
• • Bone
  • • Primary hyperparathyroidism in pregnancy

      ea0034p1
    • Primary hyperparathyroidism in pregnancy presenting as hyperemesis

      ea0034p2
    • The utility of bone turnover markers in Paget's disease of bone

      ea0034p3
    • An audit of the clinical indications for initiation of Denosumab as a treatment for Osteoporosis in a secondary care clinic

      ea0034p4
    • Value of sequential 25-hydroxyvitamin D measurements prior to denosumab and zoledronic acid treatment

      ea0034p5
    • Impact of vitamin D replacement in patients with primary hyperparathyroidism and co-existing vitamin D deficiency

      ea0034p6
    • Monitoring the bisphosphonate treatment holiday

      ea0034p7
    • Liraglutide, a glucagon-like peptide-1 receptor agonist, improves bone mass and architecture in ovariectomised mice

      ea0034p8
    • Pre-operative localisation studies in primary hyperparathyroidism: concordance with surgical findings and histology

      ea0034p9
    • Abstract unavailable

      ea0034p10
    • Unusual cause of hypocalcemia

      ea0034p11
    • The influence of gender on the bone health of adolescent patients with hormonal deficiencies

      ea0034p12
    • Mutational analysis of the adaptor protein 2 sigma subunit (AP2S1) gene: search for autosomal dominant hypocalcaemia type 3 (ADH3)

      ea0034p13
    • Clinical studies of adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 reveal genotype-phenotype correlations and effectiveness of cinacalcet

      ea0034p14
    • Identification of 12 adaptor protein-2 sigma 2 subunit mutations in familial hypocalciuric hypercalcaemia type 3 and expansion of phenotypic spectrum.

      ea0034p15
    • Role of cortisol in the pathogenesis of postmenopausal osteoporosis: relationship to bone structure

      ea0034p16
    • The calcilytic NPS2143 rectifies the gain-of-function associated with G-protein [alpha] 11 mutations causing autosomal dominant hypocalcaemia type 2

      ea0034p17
    • Baseline characteristics of patients presenting with primary hyperparathyroidism

      ea0034p18
    • Treatment of vitamin D deficiency in primary hyperparathyroidism (PHPT) with different vitamin D preparations.

      ea0034p19
    • Is parathyroid hormone venous sampling useful? Correlation of parathyroid hormone selective venous sampling and histopathological results in patients who underwent parathyroidectomy between 2006 and 2013

      ea0034p20
    • Predictors of postoperative hypocalcaemia in parathyroidectomy patients: local audit

      ea0034p21
    • A rare germline Leu63Pro missense mutation in CDC73 resulting in familial primary hyperparathyroidism with variable phenotype

      ea0034p22
    • Hypogonadism masquerading as metabolic bone disease in an young male

      ea0034p23
    • Unusual parathyroid location: a case of primary hyperparathyroidism with failed right parathyroidectomy

      ea0034p24
    • Is the response to high dose oral vitamin D replacement predictable?

      ea0034p25
    • Functional read out of defective osteoclast function in an in vitro model of Gaucher's disease

      ea0034p26
    • The diagnosis of osteoporosis among South Indian male and female subjects with low impact hip fracture and comparison between Indian Council of Medical Research and Caucasian Bone Mineral Density Databases

      ea0034p27
    • Evaluation of a glucocorticoid-induced osteoporosis model using ImageJ

      ea0034p28
    • The worlds of primary and secondary hyperparathyroidism often collide; what effect do variable regimens of supplementing vitamin D have in primary hyperparathyroidism?

      ea0034p29
    • An ectopic parathyroid adenoma presenting with reduced conscious level and severe hypertension

      ea0034p30
  • Clinical biochemistry
  • • Effects of light at night and rotating shift on circadian pattern of neuroendocrine chronomolecules

      ea0034p31
    • Limitations of dexamethasone suppression tests for Cushing's disease: a reminder!

      ea0034p32
    • Are we investigating and managing hyponatremia in hospitalised patients properly: a re-audit

      ea0034p33
    • A routine combined LC-MS/MS assay for male androgens

      ea0034p34
    • Urinary kisspeptin as a novel marker of pregnancy

      ea0034p35
    • The effects of climate on the incidence of thiazide diuretic induced hyponatraemia in the UK

      ea0034p36
    • Generation of a long acting GCSF for treatment of neutropenia and stem cell harvest

      ea0034p37
    • Hypercalcaemia referrals from primary care: a retrospective audit

      ea0034p38
    • Development of a LC-MS/MS method for the measurement of serum 17-hydroxyprogesterone during the follicular and luteal phases of the menstrual cycle

      ea0034p39
    • Audit on short synacthen test: are 30 and 60 min samples necessary?

      ea0034p40
    • A comparison of calculated bioavailable testosterone with calculated free testosterone

      ea0034p41
    • Urinary 3-methoxytyramine as a biomarker of phaeochromocytoma and paraganglioma tumours

      ea0034p42
    • Evaluation of the efficacy of transdermal delivery of chloroquine on Plasmodium berghei-infected male Sprague-Dawley rats: effects on blood glucose and renal electrolyte handling

      ea0034p43
    • Measurement of dexamethasone by LC-MS/MS after a 1 mg overnight dexamethasone suppression test

      ea0034p44
    • Serum 5HIAA: a better biomarker than urine for detecting and monitoring neuroendocrine tumours?

      ea0034p45
    • High testosterone? Look again!

      ea0034p46
    • Vitamin D status in patients visiting a large teaching hospital

      ea0034p47
    • Development of a whole blood assay for the LC-MS/MS measurement of 5-hydroxyindole acetic acid

      ea0034p48
    • Do we need method specific cortisol cut off limits for dynamic function tests?

      ea0034p49
    • Reference ranges for salivary steroid measurement during short synacthen tests

      ea0034p50
    • Hyponatraemia prior to discharge from hospital after a general medical admission is associated with a significantly increased risk of readmission within 28 days

      ea0034p51
  • Clinical practice/governance and case reports
  • • Clinical application of the levothyroxine absorption test

      ea0034p52
    • Recurrent hypomagnesaemia, tackling modifiable risk factors

      ea0034p53
    • Thyrotoxicosis after severe hypothyroidism in a patient with a history of Hodgkin's lymphoma and neck irradiation

      ea0034p54
    • Large testicular adrenal rest tumours in a patient with congenital adrenal hyperplasia: a consequence of poor drug compliance

      ea0034p55
    • A case of precocious puberty in a 4-year-old boy: differential diagnosis and treatment goals

      ea0034p56
    • Fixed dose radioactive iodine treatment for hyperthyroidism: experience of a district general hospital

      ea0034p57
    • Investigation of inpatient hyponatraemia in a teaching hospital

      ea0034p58
    • Unexpected adrenocortical carcinoma 8 years after diagnosis of adrenal incidentaloma

      ea0034p59
    • Characteristics, comorbidities and aetiology of hospitalised patients with hyponatraemia

      ea0034p60
    • Endocrine complications of thalassemia and its treatment: a local experience

      ea0034p61
    • Juvenile granulosa cell tumour of the ovary presenting with hyperprolactinaemic amenorrhoea and galactorrhoea

      ea0034p62
    • Analysis of hyponatraemic inpatients who died in a teaching hospital

      ea0034p63
    • Elevated hounsfield units and large tumour size on radiological imaging are both suggestive of functionality in incidental adrenal tumours

      ea0034p64
    • Spontaneous hypoglycaemia in a non-diabetic patient with insulin antibodies

      ea0034p65
    • Severe hypercalcaemia requiring emergency haemodialysis due to postpartum hypophysitis and thyroiditis

      ea0034p66
    • Parathyroid adenoma presenting solely as acute necrotising pancreatitis in an adolescent girl

      ea0034p67
    • Pseudo-secondary hyperparathyroidism due to vitamin D deficiency and coexisting familial hypocalciuric hypercalcaemia

      ea0034p68
    • An unusual cause and an unusual complication of Cushing's syndrome

      ea0034p69
    • Not every Gestational Diabetes is Mellitus!

      ea0034p70
    • A rare endocrine cause of severe resistant hypoglycaemia

      ea0034p71
    • Enigma of an 18 year Acromegalic Window: what your mind knows but eyes may still miss?

      ea0034p72
    • Adrenal masses-a bleeding problem

      ea0034p73
    • Abstract unavailable

      ea0034p74
    • Stuttering priapism

      ea0034p75
    • Recovery of adrenal function in confirmed Addison's disease

      ea0034p76
    • Hypercalcaemia: a mixed family picture

      ea0034p77
    • Severe hypercalcaemia and acute kidney injury secondary to Graves' thyrotoxicosis

      ea0034p78
    • Patient feedback on receiving copies of clinic correspondence

      ea0034p79
    • Carbimazole induced agranulocytosis: a case report in the setting of a young female, on low dose and duration of treatment of more than one year

      ea0034p80
    • The patient with broken heart

      ea0034p81
    • Do you know where the hypo box on the ward is? A revealing audit...

      ea0034p82
    • Plasma 25-hydroxycholecalciferol before and after supplementation in paediatric oncology patients from Scotland: a time-series cross-sectional study

      ea0034p83
    • Long-term follow-up of patients treated with tolvaptan for resistant hyponatraemia

      ea0034p84
    • A rare cause of primary adrenal insufficiency

      ea0034p85
    • A feminising adrenocortical carcinoma

      ea0034p86
    • Look before you leap... An adrenal mass and elevated metadrenalines may not be phaeochromocytoma

      ea0034p87
    • Is demeclocycline safe and effective in the treatment of SIADH?

      ea0034p88
    • Low dose tolvpatan (7.5 mg) is effective in the management of SIADH in oncology patients (results from a retrospective audit at The Christie Hospital and Wythenshawe Pulmonary Oncology Unit)

      ea0034p89
    • Teriparatide infusion for post-thyroidectomy hypocalcaemia: a case report

      ea0034p90
    • Kallmann syndrome, gender dysphoria, thrombophilia and multiple sclerosis: a complex case report

      ea0034p91
    • An audit of clinical follow-up and management of adult patients with Turner's syndrome at the Royal Devon and Exeter

      ea0034p92
    • Can a random cortisol predict outcome of short Synacthen test in non-acute patients with low pre-test probability?

      ea0034p93
    • An unusual case of recurrent hypercalcaemia: sleeping parathyroid hyperplasia?

      ea0034p94
    • Hypokalaemia attributed to liquorice use: not Allsorted!

      ea0034p95
    • Pre clinic tests accelerate decision making, reduce delays in treatment and are highly popular with endocrinology patients and staff

      ea0034p96
    • Carbimazole-induced antineutrophil cytoplasmic antibody positive vasculitis: a case report

      ea0034p97
    • Outcomes following pituitary surgery: a single centre audit

      ea0034p98
    • Hyperparathyroidism in early pregnancy: a case report

      ea0034p99
    • Distinguishing between primary hyperparathyroidism and familial hypocalciuric hypercalcaemia: the role of genetic testing in patient with equivocal results

      ea0034p100
    • Efficacy and safety of doxazosin in perioperative management of phaeochromocytoma

      ea0034p101
    • Are we appropriately referring patients for short synacthen testing?

      ea0034p102
    • The use of s.c. denosumab for cases of hypercalcaemia refractory to i.v. bisphosphonate therapy

      ea0034p103
    • Localised Charcot of the Hallux

      ea0034p104
    • Phaeochromocytomas and paragangliomas: a 20 year experience

      ea0034p105
    • Autoimmune adrenal insufficiency presenting as severe hypercalcaemia

      ea0034p106
    • Somatostatin analogue therapy with good biochemical response in a patient with ectopic ACTH secretion due to high grade metastatic neuroendocrine tumour

      ea0034p107
    • Improving the quality of endocrinology teaching to clinical medical students

      ea0034p108
    • An audit into the screening tests used for Cushing's syndrome

      ea0034p109
    • Testicular adrenal axis lymphoma

      ea0034p110
    • A rare case of Cushing's syndrome caused by 'cyclical' ectopic ACTH secretion

      ea0034p111
    • Management of hyponatremia in secondary care

      ea0034p112
    • A case of severe hypercalcaemia

      ea0034p113
    • Baseline assessment of patients referred for 'metabolic surgery': managing the myriad of metabolic abnormalities

      ea0034p114
    • Detecting vitamin D deficiency in South Asians: is a population or targeted method better?

      ea0034p115
    • Endocrinology in a district general hospital; it's not all thyroid disease

      ea0034p116
    • Polycythaemia is a common side-effect of testosterone therapy, regardless of treatment mode, and careful monitoring of haematological indices is required

      ea0034p117
    • Gastrinoma: difficult to diagnose difficult to treat

      ea0034p118
    • Severe hyponatraemia, hypokalaemia and associated seizure following the administration of sodium picosulfate/magnesium citrate (picolax): a case report

      ea0034p119
    • Bilateral adrenal hyperplasia: a rare cause of Cushing's syndrome in chidren

      ea0034p120
    • Micrometastases in a paraganglioma

      ea0034p121
    • Mitotane ameliorates testostoxicosis due to metastatic Leydig cell tumour

      ea0034p122
    • Hypomagnesaemia during proton pump inhibitor therapy causing functional hypoparathyroidism

      ea0034p123
    • Anti-GAD antibody encephalitis: a potentially treatable syndrome

      ea0034p124
    • Intravascular pituitary invasion by large B-cell lymphoma is a rare cause of SIADH and hypopituitarism; a case report

      ea0034p125
    • Double trouble: pseudo-phaeochromocytoma in a patient with adrenocortical cancer

      ea0034p126
    • Audit on investigations and diagnosis of hyponatremia in in-patients at a district general hospital

      ea0034p127
    • Three cases of octogenarians with Cushing's syndrome

      ea0034p128
    • Spontaneous hypoglycaemia induced by ACE-inhibitor: a case report

      ea0034p129
    • The role of genetic analysis in the diagnosis of familial hypocalciuric hypercalcaemia

      ea0034p130
    • Epidural abscess as a complication of infected diabetic foot ulcers: a case report.

      ea0034p131
    • Alternating high and low TSH levels post subacute thyroiditis

      ea0034p132
    • Pituitary apoplexy during a second pregnancy in a woman with prolactinoma

      ea0034p133
    • Endocrine considerations in ever-improving HIV-related mortality outcomes: a clinical perspective

      ea0034p134
    • Next generation sequencing approach for molecular genetic diagnosis of familial partial lipodystrophy

      ea0034p135
    • The H-syndrome and next generation sequencing for molecular genetic diagnosis

      ea0034p136
    • Adrenal incidentalomas, a district hospital perspective

      ea0034p137
    • Acute confusional state in the thyroid clinic: autoimmunity as a multi-edge knife

      ea0034p138
    • Jumping the gun: an audit of adrenal biopsies in a tertiary referral centre

      ea0034p139
    • Is levothyroxine availability enhanced by grapes?

      ea0034p140
    • Granulomatosis with polyangiitis presenting as a pituitary lesion

      ea0034p141
    • A case of hypoadrenalism

      ea0034p142
    • Mayer-Rokitansky-Kuster-Hauser syndrome and pituitary adenoma: a co-incidence?

      ea0034p143
    • Madness on the medical ward: ectopic ACTH producing tumour

      ea0034p144
    • Training needs in adolescent health and transition in paediatric and adult trainees in diabetes and endocrinology in the UK

      ea0034p145
    • Delayed hypocalcaemia following treatment of malignant hypercalcaemia with denosumab

      ea0034p146
    • Non islet cell tumour hypoglycaemia: management strategies for a rare and challenging condition

      ea0034p147
    • Diabetes: the forgotten complication of parathyroidectomy

      ea0034p148
    • Adrenocortical carcinoma, where's the delay?

      ea0034p149
    • Tertiary hyperparathyroidism: a long-term complication of pseudohypoparathyroidism type 1b?

      ea0034p150
    • Liraglutide as an effective therapeutic agent in a patient with Prader Willi syndrome and type 2 diabetes

      ea0034p151
    • Cushing's disease with hepatic adrenal rests

      ea0034p152
    • The prevalence and mortality in hospitalised patients with mild, moderate, and severe hyponatremia

      ea0034p153
    • Profound hyponatraemia secondary to indapamide

      ea0034p154
  • Cytokines and growth factors
  • • Modelling hepatic encephalopathy in vitro: molecular and functional consequences of hyperammonaemia in C6 glioma cells

      ea0034p155
    • Spatial expression profiling reveals tissue-specific sexual dimorphism of the natriuretic peptide system in mice

      ea0034p156
    • The remote organ effects of acute kidney injury in a porcine model

      ea0034p157
  • Growth and development
  • • A novel gene affecting the timing of puberty

      ea0034p158
    • Identification and characterisation of human foetal adrenocortical progenitor cells

      ea0034p159
    • Relationships between final height and health outcomes in adults with congenital adrenal hyperplasia: United Kingdom Congenital adrenal Hyperplasia Adult Study Executive (CaHASE)

      ea0034p160
    • CUL7, OBSL1 and CCDC8 modulate alternative splicing of exon 11 of the insulin receptor gene

      ea0034p161
    • Abstract unavailable

      ea0034p162
    • C-type natriuretic peptide regulates growth and pituitary development in the zebrafish (Danio rerio)

      ea0034p163
    • Distinct gene expression is associated with epigenetic and growth-related network modules in relation to gender differences in the timing of the pubertal growth spurt

      ea0034p164
    • Altered frequency of sequence variants in growth-related genes in children with short stature

      ea0034p165
    • Differential effects of grazing and meal feeding on skeletal growth and femoral strength in male rats

      ea0034p166
  • Neoplasia, cancer and late effects
  • • Calycosin suppresses breast cancer cell growth via ER[beta]-mediated inhibition of IGF1R pathway

      ea0034p167
    • A challenging case of hypokalaemic Cushing's crisis

      ea0034p168
    • Investigating neuroendocrine markers of small cell lung cancer

      ea0034p169
    • Comparison of HbA1c and oral glucose tolerance testing for the diagnosis of patients with and at risk of diabetes among long-term bone marrow transplant survivors

      ea0034p170
    • Neuroendocrine biomarkers change with treatment in small cell lung cancer

      ea0034p171
    • Late presentation predicts endocrine dysfunction in patients with Langerhans cell histiocytosis: a retrospective analysis of the West of Scotland LCH service 1998-2012

      ea0034p172
    • The first reported mutations in the pituitary tumor-transforming gene binding factor

      ea0034p173
    • Bromodomain inhibitors reduce proliferation and increase apoptosis of human neuroendocrine tumour cells

      ea0034p174
    • Adrenocortical cancer: rare but gloomy cause of adrenal lesions

      ea0034p175
    • Metastatic paraganglioma with unknown genetics: to screen or not to screen the family?

      ea0034p176
    • Clinical dilemmas in diagnosing pheochromocytoma

      ea0034p177
    • Inhibition of radioiodine uptake by PBF in breast cells is consistent with sodium-iodide symporter repression in the thyroid

      ea0034p178
    • Expression modulation of tumour necrosis factor [alpha] and tumour necrosis factor receptor 1 genes in breast cancer cell lines (MCF-7) by some selected indigenous cytotoxic plants

      ea0034p179
    • Characteristics of 'foregut' carcinoid tumours occurring in multiple endocrine neoplasia type 1

      ea0034p180
    • Inherited mutations in the SDH complex increase metastatic malignant potential of paragnglioma and phaeochromocytoma tumours

      ea0034p181
    • Pre-clinical assessment of the impact of Erlotinib on adrenocortical cancer cells proliferation

      ea0034p182
    • Long-term negative effects in young cancer survivors: metabolic disorders in the patients after complex treatment for brain tumors and acute lymphoblastic leukemia in childhood and adolescence

      ea0034p183
    • Diagnosis of adrenocortical carcinoma; urinary steroid profiles measured by GC:MS

      ea0034p184
    • A rare adrenal lieomyosarcome in a subject with lupus and the antiphospholipid syndrome

      ea0034p185
    • RET genetic screening in patients with multiple endocrine neoplasia type 2 and medullary thyroid carcinoma: experience of the Exeter Molecular Genetics Laboratory

      ea0034p186
    • MIBG-avidity in genetically distinct phaeochromocytoma and paraganglioma populations

      ea0034p187
    • SDHB surveillance regime: a single UK institution experience

      ea0034p188
    • Multiple endocrine neoplasia type 2A in a large family with a C620G mutation of the RET proto-oncogene: diagnostic, treatment, and ethical challenges

      ea0034p189
    • An incidental diagnosis...

      ea0034p190
    • ATR kinase function is modulated by the proto-oncogene PBF

      ea0034p191
  • Nursing practise
  • • Steroid group education: developing a curriculum ensures good nursing practice is maintained

      ea0034p192
    • Time taken for GH-treated adolescent patients, transitioning to adult services, to reach IGF1 levels within the upper normal range: do we need to monitor more frequently?

      ea0034p193
    • Life, death and modern technology: an update

      ea0034p194
    • Intervention of ward visits by an endocrine nurse specialist and a protocol and in the management of hyponatraemia

      ea0034p195
    • Treating vitamin D deficiency in coeliac patients

      ea0034p196
    • Integrating a new drug into clinical practice and enhancing the patient experience

      ea0034p197
    • Emergency hydrocortisone kits: assessment of knowledge and skills of patients and family

      ea0034p198
  • Obesity, diabetes, metabolism and cardiovascular
  • • The effect of L-cysteine on appetite in humans

      ea0034p199
    • Analysis of serum FTO level and related factors in obese and T2DM patients

      ea0034p200
    • Associations between regional body fat distribution and homocysteine levels in type 2 diabetes with coronary atherosclerosis patients

      ea0034p201
    • An opinion survey in Eastern Ghana: health behaviours and knowledge of diabetes in diagnosed diabetes mellitus type 2 patients

      ea0034p202
    • Effects of transdermally delivered insulin on some selected metabolic parameters of streptozotocin-induced diabetic male Sprague-Dawley rats

      ea0034p203
    • Early insulin therapy: a new treatment approach for type-2 diabetes mellitus with HbA1c[gt]7%

      ea0034p204
    • Cross-sectional survey of depression and anxiety in a clinical diabetes population: prevalence and role in blood sugar control

      ea0034p205
    • Dark chocolate rich in polyphenols improves insulin sensitivity in the adult non-diabetic population

      ea0034p206
    • Effect of H. gordonii on regulatory peptides under short-term calorie restriction

      ea0034p207
    • Abnormal glucocorticoid metabolism in horses with metabolic syndrome

      ea0034p208
    • An audit of patients with diabetes attending accident and emergency with severe hypoglycaemia

      ea0034p209
    • Predictive clinical variables for periodontitis in type 2 diabetic subjects with poor glycemic control.

      ea0034p210
    • Impact of the serum testosterone on the metabolic syndrome in Chinese young and middle-agd men with type 2 diabetes mellitus

      ea0034p211
    • Metabolic improvement after bariatric surgery: an overview from a single tertiary centre

      ea0034p212
    • Renal function variation after bariatric surgery: which measurement do we rely on?

      ea0034p213
    • Chemerin as a potential screening marker for sub-clinical diabetes?

      ea0034p214
    • The salt-inducible kinases: gatekeeper of hepatic gluconeogenesis

      ea0034p215
    • Maturity onset diabetes of young type 5

      ea0034p216
    • Obstructive sleep apnoea syndrome and type 2 diabetes

      ea0034p217
    • Young women with polycystic ovary syndrome have increased concentrations of circulating annexin V-positive microparticles derived predominantly from platelets

      ea0034p218
    • Quality improvement for patients with type 2 diabetes

      ea0034p219
    • Central arterial stiffness and diastolic dysfunction are not increased in young women with PCOS but are associated with insulin resistance and abdominal obesity

      ea0034p220
    • An evaluation of knowledge and understanding of HbA1c in diabetes patients in a secondary care setting

      ea0034p221
    • Joint predictability of physical activity and bodyweight on health-related quality of life among Nigerian type 2 diabetes

      ea0034p222
    • A 3-month low fat diet leads to significant lipid profile improvement in obese T2DM Saudi subjects, without substantial weight loss, and the capacity to manage a damaging high-fat meal challenge more appropriately post intervention

      ea0034p223
    • DLK1/PREF1 prevents hepatosteatosis by elevating pituitary GH secretion

      ea0034p224
    • Outcomes of bariatric surgery in men versus women: a matched observational cohort analysis

      ea0034p225
    • Meal size and frequency influences metabolic endotoxaemia and inflammatory risk but has no effect on diet induced thermogenesis in either lean or obese subjects

      ea0034p226
    • Screening and diagnosis of gestational diabetes: impact of age, BMI and adipokines

      ea0034p227
    • Abstract unavailable

      ea0034p228
    • The effects of treatment with Liraglutide on atherothrombotic risk in obese young women with polycystic ovary syndrome and controls

      ea0034p229
    • MIneral nutrients and metabolic health: data on nigerian local dishes

      ea0034p230
    • EZH2 regulates responses of endothelial cells under hypoxia and during tissue regeneration following limb ischemia

      ea0034p231
    • High incidence of cardiac involvement in patients diagnosed with phaeochromocytoma: a clinical study using cardiovascular magnetic resonance imaging

      ea0034p232
    • Microparticle profile in patients with type 2 diabetes

      ea0034p233
    • Expression of GLP1 receptors throughout the mouse brain using a novel transgenic mouse model

      ea0034p234
    • Novel syndromes of hypoinsulinaemic, hypoketotic hypoglycaemia

      ea0034p235
    • The characteristics of a patient population with extreme and complex obesity attending a specialist weight management service

      ea0034p236
    • Coffee attenuates induction of insulin resistance in high sucrose-diet fed rats

      ea0034p237
    • Systemic triglycerides as a key determinant of TLR regulated inflammatory risk in human adipose tissue post bariatric surgical intervention and weight loss

      ea0034p238
    • Upregulation of AKR1C3 expression by insulin in a human differentiated preadipocyte cell line

      ea0034p239
    • The outcome results in patients with type 2 diabetes mellitus and obesity after either adjustable gastric banding or Roux-en-Y gastric bypass

      ea0034p240
    • Diabetes in pregnancy and birth weight: differential effects due to ethnicity in a real-life observational study

      ea0034p241
    • Evolutionary conserved novel targets of NGN3, located on the short arm of chromosome 20, may have a role in the development of the endocrine pancreas

      ea0034p242
    • Decreased brain 11[beta]-HSD1 expression following inflammation; a role in regulating brain energy homeostasis?

      ea0034p243
    • Capillary blood glucose monitoring and ambulatory peritoneal dialysis: reassuring the patient

      ea0034p244
    • Case report: the role of somatostatin analogue therapy in nesidioblastosis following Roux-en-Y bypass surgery

      ea0034p245
    • Impact of chronic heart failure on adipose tissue functional plasticity: a role for fatty acids?

      ea0034p246
    • Maternal metabolic adaptations in pregnancy are associated with altered circadian rhythmicity

      ea0034p247
    • Abstract unavailable

      ea0034p248
    • Derivatisation of estrogens enhances specificity and sensitivity of analysis by liquid chromatography tandem mass spectrometry

      ea0034p249
    • Virally delivered target-specific optogenetic stimulation of PPG neurons in the nucleus of the solitary tract

      ea0034p250
    • Metformin and acute kidney injury: is it the culprit?

      ea0034p251
    • The role of glucocorticoid metabolism in bile acid homeostasis

      ea0034p252
    • Gitelman syndrome

      ea0034p253
    • Abstract unavailable

      ea0034p254
    • Serum ferritin levels are correlated with total adiposity, but not BMI in obese males

      ea0034p255
    • Ventricular dysfunction in the new born secondary to maternal vitamin D deficiency

      ea0034p256
    • Contribution of hepatic liver X receptor to the adaptations in maternal lipid metabolism during pregnancy

      ea0034p257
    • High serum amylase a contraindication to GLP1 analogue treatment?

      ea0034p258
    • Decrums disease: an unusual case of bilateral adrenal lipomas

      ea0034p259
    • Longitudinal changes in glucocorticoid metabolism predict the development of metabolic phenotype

      ea0034p260
    • Abstract unavailable

      ea0034p261
    • Elevated cord leptin from low B12 mothers predicts birth weight

      ea0034p262
    • Renalase a key regulator of brown adipose tissue activity

      ea0034p263
    • Bariatric surgery for hypothalamic obesity: case series report

      ea0034p264
    • Depletion of glucose-6-phosphate transporter impacts SR calcium homeostasis in muscle

      ea0034p265
    • Breaking NAD+: investigating NMRK2 as a regulator of muscle adaptation through NAD+ salvage

      ea0034p266
    • 11[beta] HSD1KO mice resist aged associated decline in markers of brown adipose tissue function

      ea0034p267
    • H6PDH deficiency in muscle impacts amino acid metabolism

      ea0034p268
    • Unfolded protein response in adipose tissue of obese diabetic women significantly improved 6 months post bariatric surgery, irrespective of malabsorptive or bypass operation type and correlates with plasma glucose concentration

      ea0034p269
    • Does TCF7L2 polymorphisms increase the risk of gestational diabetes mellitus in South Indian population?

      ea0034p270
    • Evaluating [beta]-hydroxybutyrate as indicator for early termination of 72 h fast for spontaneous hypoglycaemia

      ea0034p271
    • Liver fibrosis is common in Alstrom syndrome and can be identified using non-invasive tests

      ea0034p272
    • Familial adult hyperinsulinism due to genetic glucokinase activation: implications for therapeutic use of glucokinase activators

      ea0034p273
    • Metabolic pathway analysis in choline and methionine deficient mice: new insights into the mechanism of steatosis and insulin resistance

      ea0034p274
    • Evaluation of a crude extract administration of Cnidoscolus chayamansa in normal and diabetic Wistar rats

      ea0034p275
    • A pathway to investigate and manage patients complaining of symptoms suggestive of hypoglycaemia post Roux-en-Y gastric bypass surgery

      ea0034p276
    • Proliferative retinopathy in pregnancy after bariatric surgery

      ea0034p277
    • Therapeutic durability of the GLP1-based therapy Liraglutide in patients with type 2 diabetes mellitus

      ea0034p278
  • Pituitary
  • • An unusual cause of pituitary apoplexy

      ea0034p279
    • Pituitary metastasis from CLL - an extremely rare case

      ea0034p280
    • Painful third nerve palsy caused by primary pituitary lymphoma associated with apoplectic pituitary adenoma

      ea0034p281
    • Lack of Fpr2/Fpr3 receptors alters the structure and function of pituitary corticotrophs

      ea0034p282
    • A deficit of dystrophin 71 leads to disorder in vasopressin and oxytocin production in the magnocellular neurons

      ea0034p283
    • The effect of pregnancy on hyperprolactinaemia: a 5-year retrospective observational study

      ea0034p284
    • Diabetes insipidus in Erdheim-Chester disease

      ea0034p285
    • The gonadotroph natriuretic peptide system is sensitive to pulsatile GnRH stimulation: insights into CNP/GC-B signalling in gonadotroph function

      ea0034p286
    • An evolution of clinical practice: the impact of changes in clinical management of non-functioning pituitary adenomas on long-term pituitary function and risk of recurrence

      ea0034p287
    • A case of pancytopenia due to isolated ACTH deficiency successfully treated with hydrocortisone

      ea0034p288
    • Comparison of acute and subacute pituitary tumour apoplexy

      ea0034p289
    • Newer dopaminergic agents cause minimal endocrine effects in subjects with idiopathic Parkinson's disease

      ea0034p290
    • Chronic glucocorticoid exposure inhibits expression of the pomc activator, tpit, by inducing de-novo DNA methylation

      ea0034p291
    • Follow-up, surgery and proton beam therapy for a pituitary sella chondrosarcoma

      ea0034p292
    • GH excess of unknown origin

      ea0034p293
    • Hypopituitarism from Hyderabad

      ea0034p294
    • Can 0900 h serum cortisol levels be used to predict patient's response to the insulin tolerance test?

      ea0034p295
    • The challenge of diagnosing Langerhan cell histiocytosis as the cause of a hypothalamic lesion presenting with diabetes insipidus

      ea0034p296
    • Just another 'incidental finding'?

      ea0034p297
    • Could GH deficiency exacerbate insulinoma?

      ea0034p298
    • Pituitary tuberculosis

      ea0034p299
    • Immunohistochemical features of PANCH tumour, a mixed pituitary adenoma/gangliocytoma, a rare cause of acromegaly

      ea0034p300
    • Sheehan's syndrome: end of 15 years of hardship

      ea0034p301
    • Primary polydipsia in a family with a known mutation in the AVP gene

      ea0034p302
    • Differential p120 isoform distribution and splicing regulator ESRP1 expression distinguishes sparsely and densely granulated somatotroph adenomas

      ea0034p303
    • Disordered sleep architecture is a common finding in acromegaly

      ea0034p304
    • The effects of kisspeptin-54 administration on GH, prolactin, and TSH secretion in healthy women

      ea0034p305
    • One year pituitary function follow-up in survivors of severe brain injury presenting at a regional neurosurgical centre

      ea0034p306
    • The incidence of hypopituitarism in post interventional subarachnoid haemorrhage (SAH) survivors in a tertiary neurosurgical unit

      ea0034p307
    • Inhibition of lipolysis improves peripheral and hepatic insulin sensitivity and restores first phase insulin response in patients with acromegaly

      ea0034p308
    • Acromegaly in a treated prolactinoma

      ea0034p309
    • The effect of somatostatin analogues on the hypothalamo-pituitary-thyroid axis and peripheral thyroid hormone dependent tissues in patients with thyrotropin secreting pituitary tumours

      ea0034p310
    • A medically managed pituitary tumour and ovarian tumours in a young female

      ea0034p311
    • Isolated 6th nerve palsy, a surprising complication of acromegaly

      ea0034p312
    • Optochiasmal cavernoma presenting with secondary hypogonadism: a case report

      ea0034p313
    • Analysis of the AIP gene promoter

      ea0034p314
  • Reproduction
  • • Protective role of Nigerian honey on sperm indices and testis in sucrose-fed rat

      ea0034p315
    • Effects of bovine somatotropin on libido, serum testosterone, hematology and certain biochemical metabolites of Sahiwal bulls

      ea0034p316
    • Gestational diabetes and polycystic ovary syndrome

      ea0034p317
    • Plant molecules quercetin and resveratrol can affect ovarian cells and invert FSH action

      ea0034p318
    • Fetal glucocorticoid overexposure impacts on germline epigenetic reprogramming in the rat

      ea0034p319
    • Post-endocytic sorting of the LH receptor is mediated by a novel APPL1 dependent mechanism

      ea0034p320
    • Fertility and pregnancy outcomes for patients with polycystic ovary syndrome in the UK: a retrospective observational study

      ea0034p321
    • In the mouse ovary AMH expression is independent of androgen physiology

      ea0034p322
    • Interaction of androgen with IGF signalling in preantral follicle development in the mouse ovary

      ea0034p323
    • Regulation of implantation by interaction between the IGF receptor (IGF1R) and miR-145

      ea0034p324
    • Renal anomalies in Kallmann syndrome, an uncommon association

      ea0034p325
    • miR-145 is associated with placental growth in mice

      ea0034p326
    • Glial cells missing 1 transactivates the equine chorionic gonadotrophin beta promoter

      ea0034p327
    • Hypoxia induces terminal differentiation of primary trophoblast cells in vitro

      ea0034p328
    • A rare cause of infertility

      ea0034p329
    • Transforming growth factor-[beta] superfamily signalling and its role in the pathogenesis of heavy menstrual bleeding

      ea0034p330
    • Effect of endometrial thickness on pregnancy outcome after ICSI

      ea0034p331
    • Regulation of the LH/CG receptor signalling in human endometrium

      ea0034p332
    • Steroid hormones regulate cyclical expression of osteopontin and CD44 in the ovine endometrium

      ea0034p333
    • Oestrogen implant improves symptoms of hypogonadism and lipid profile in transwomen

      ea0034p334
    • Testosterone implant therapy: efficacy and safety in transmen and native men with hypogondism

      ea0034p335
    • Elevation of HRPE773 (ZG16B) expression in amnion at term and in human ectocervical cell lines treated with inflammatory mediators is consistent with a function in innate immunity

      ea0034p336
    • Maternal and cord blood serum IGF1 IGF binding protein-3, in asymmetrically small for gestational age neonates

      ea0034p337
    • The melanocortin system in the male reproductive axis

      ea0034p338
    • Hyperandrogenism secondary to ovarian hyperthecosis masked by concurrent use of an aromatase inhibitor: a case report

      ea0034p339
    • Two rare conditions in one patient: Fragile X and congenital adrenal hyperplasia

      ea0034p340
  • Steroids
  • • Defining contralateral adrenal suppression in primary aldosteronism: implications for diagnosis and outcome

      ea0034p341
    • Monitoring outcomes in congenital adrenal hyperplasia: have we been neglecting testosterone?

      ea0034p342
    • A large retrospective audit of adrenal incidentalomas

      ea0034p343
    • Biophenols-rich pomegranate extract intake inhibits salivary cortisol and 11[beta]-HSD1 activity and improves overall quality of life scores in healthy volunteers

      ea0034p344
    • Role of estrogen hormone in lipopolysaccharide: induced Alzheimer's disease in female rats; possible underlying mechanisms and modulation by progesterone hormone

      ea0034p345
    • A rapid and sensitive LC-MS/MS method for the simultaneous analysis of testosterone, androstenedione, 17-OHP, and DHEAS

      ea0034p346
    • A case of recurrent, re-admissions with severe hyperemesis gravidarum

      ea0034p347
    • The effect of green tea extracts on steroidogenesis, proliferation and apoptosis in ovarian granulosa cells

      ea0034p348
    • Hyperandrogenaemia predicts metabolic phenotype in polycystic ovary syndrome: the utility of serum androstenedione

      ea0034p349
    • Upregulation of subcutaneous adipose AKR1C3 expression in obese females: evidence for depot- and sex-specific effects

      ea0034p350
    • High 11[beta]-HSD1 activity is associated with progression to rheumatoid arthritis in patients first presenting with inflammatory arthritis

      ea0034p351
    • Urinary steroid profiling by Gas-Chromatography Mass-Spectrometry (GC-MS) is not helpful in the diagnosis of Cushing's Syndrome

      ea0034p352
    • A novel UPLC-MS/MS method to extract and quantify sulphated and non-sulphated oestrogens automatically optimised using MUSCLE software

      ea0034p353
    • Dexamethasone-related adrenal insufficiency in patients with solid brain tumours

      ea0034p354
    • Patient education and steroid replacement regimens in adrenal insufficiency

      ea0034p355
    • Evaluating progesterone as a novel neuroprotective drug after ocular injury

      ea0034p356
    • Steroid sulfatase contributes to systemic androgen activation in pre-pubertal boys: lessons from steroid sulfatase deficiency

      ea0034p357
    • Glucocorticoid receptor interactome

      ea0034p358
    • Does recurrent hypoglycaemia, a known activator of the HPA axis, alter the diurnal pattern of cortisol release?

      ea0034p359
    • Systemic availability of placental growth factor correlates with urinary tetrahydroaldosterone excretion in normal and preeclamptic pregnancy

      ea0034p360
    • Endogenous androgen-mediated modulation of neointima formation is independent of vascular androgen receptor

      ea0034p361
    • An audit on the outcomes of bloodspot 17-OHP results on the management of patients with CAH

      ea0034p362
    • Androgen receptor over expression drives lipid accumulation in human hepatocytes

      ea0034p363
    • Bioinformatic analysis of altered microRNA production in normal adrenal tissue and aldosterone-producing adenoma

      ea0034p364
    • 11C-metomidate PET-CT in primary hyperaldosteronism: a valuable alternative to AVS

      ea0034p365
    • Testosterone regulates glucose control in liver and muscle of Tfm mice as a mechanism to improve type 2 diabetes

      ea0034p366
    • The endocrine response to severe trauma: the Steroids and Immunity from injury to Rehabilitation (SIR) study

      ea0034p367
    • Glucocorticoid activation in muscle by 11[beta]-hydroxysteroid dehydrogenase type 1: contributions to inflammatory muscle wasting

      ea0034p368
    • Abstract unavailable

      ea0034p369
    • A very late and unusual presentation of congenital adrenal hyperplasia

      ea0034p370
    • Enhanced expression of hepatic inflammatory markers in 11[beta]-hydroxysteroid dehydrogenase type 1 knockout mice fed a steatogenic diet

      ea0034p371
    • Cushing's syndrome, missed in pregnancy

      ea0034p372
    • Dutasteride and 5[alpha]-reductase type 1 activity: for androgens only?

      ea0034p373
    • Differential impact of PAPS synthases on human sulfation pathways

      ea0034p374
    • Increased lipopolysaccharide-induced neutrophilia in mice lacking the glucocorticoid receptor in bronchial epithelial (Clara) cells

      ea0034p375
    • Blocking local glucocorticoid activation improves skin thinning and impaired healing in Cushingoid mice

      ea0034p376
    • Increased 11[beta]-hydroxysteroid dehydrogenase type 1 activity in UVB-irradiated mice

      ea0034p377
    • The Prevention of Adrenal Crisis in Stress (PACS) study: serum cortisol during elective surgery and acute trauma in comparison to stress dose hydrocortisone in adrenal insufficiency

      ea0034p378
    • Abstract unavailable

      ea0034p379
  • Thyroid
  • • Suspected DVT after thyrotoxicosis

      ea0034p380
    • Post-operative thyroiditis: an under recognised clinical phenomenon

      ea0034p381
    • Prevalence and clinical associations of calcium-sensing receptor autoantibodies in finnish APECED patients

      ea0034p382
    • Incidence of Sunitinib induced thyroid dysfunction in renal cell carcinoma: a pilot retrospective audit

      ea0034p383
    • Mis-management of medullary thyroid carcinoma leads to investigation of a non existent phaechromocytoma

      ea0034p384
    • Investigating and treating thyrotoxicosis

      ea0034p385
    • Prevalence of thyroid dysfunction in patients with rheumatoid arthritis

      ea0034p386
    • Is there a need to change how we approach a patient with hyperthyroidism?

      ea0034p387
    • A rare cause of clinical hypothyroidism: thyroid hormone resistance

      ea0034p388
    • Radioiodine therapy for thyrotoxicosis over a 2-year period: an audit

      ea0034p389
    • Factors contributing to high levothyroxine doses in primary hypothyroidism; an interventional audit of a large community database

      ea0034p390
    • Anti-thyroid drugs as treatment for neutropenia in Graves' thyrotoxicosis

      ea0034p391
    • A case of newly diagnosed hyperthyroidism in the 25th gestational week of pregnancy presented with divergent arterial hypertension

      ea0034p392
    • Deafness and goitre: think pendred

      ea0034p393
    • PBF is a component of the molecular signalling pathways that drive hyperplastic and neoplastic thyroid growth

      ea0034p394
    • Clinical outcome of radioiodine treatment for Graves' disease at a tertiary care centre

      ea0034p395
    • A highly exaggerated response to Warfarin therapy in a patient with thyrotoxicosis

      ea0034p396
    • Examination of PTTG-binding factor mRNA reveals functional miRNA target sites and exon-skipping splice variants in thyroid cells

      ea0034p397
    • Neurocognitive and CNS abnormalities in humans with defective thyroid receptor [alpha]

      ea0034p398
    • Thyrotoxicosis: a district general hospital experience compared to guidelines

      ea0034p399
    • A case of Hashimoto encephalitis in a patient with severe autoimmune hypothyroidism

      ea0034p400
    • The diagnosis of Graves' disease: diagnostic and management dilemmas

      ea0034p401
    • Severe transient hyperthyroidism and Wernicke's encephalopathy in a lady with hyperemesis gravidarum

      ea0034p402
    • Can a radiological scoring system for assessing the malignant potential of thyroid nodules be safely applied in clinical practice?

      ea0034p403
    • Thyroid nodules: Is one robust Thy2 result sufficient?

      ea0034p404
    • Scalp metastasis in follicular thyroid cancer: an atypical consequence

      ea0034p405
    • Hypoxic incubation favours the development and growth of primary human parathyroid adenoma cells

      ea0034p406
    • A mediastinal mass in a patient with thyrotoxicosis-recognising the association between thymic hyperplasia and Graves' disease

      ea0034p407
    • Thyrotoxic cardiomyopathy

      ea0034p408
    • Not to worry PET, it's not cancer

      ea0034p409
    • PTEN hamartoma syndrome: unravelling the complexities of childhood surveillance

      ea0034p410
    • A rare case of papillary thyroid cancer arising from the ovary

      ea0034p411
    • Are patients aware of the risk of agranulocytosis when taking antithyroid drugs?

      ea0034p412
    • Myxoedema coma in a patient with bipolar disorder

      ea0034p413
    • Audit of thyroid surgery outcomes for benign thyroid disease at west Hertfordshire hospitals NHS trust 2010-2012

      ea0034p414
    • Correlation between thyrotoxicosis and hepatic dysfunction in out-patient's endocrine clinic: a single centre experience

      ea0034p415
    • A case of severe hypothyroidism presenting with multi-organ failure

      ea0034p416
    • Alemtuzumab and thyroid dysfunction in patients with multiple sclerosis: experience in a university hospital

      ea0034p417
    • Consequences of an inadvertent iodine-rich diet, in previously definitively treated Graves' disease

      ea0034p418
    • A case of myxoedema coma and malnutrition

      ea0034p419
    • Is there a difference in observed bone mineral density at diagnosis of overt or subclinical thyrotoxicosis?

      ea0034p420
    • Treatment with a TR[alpha]1 antagonist increases bone mineral content

      ea0034p421
    • Neutrophil phagocytic capacity is lower in patients with abnormal thyroid function in critical illness

      ea0034p422
    • Autoimmune thyroid disease in the presence of resistance to thyroid hormone or TSH-secreting pituitary tumour: a diagnostic challenge

      ea0034p423
    • Evaluation of calcitonin as a screening tool for medullary thyroid carcinoma in patients with nodular thyroid disease

      ea0034p424
    • RET mutation negative familial medullary thyroid carcinoma: four families and literature review

      ea0034p425
    • Small papillary thyroid carcinoma: a 'benign' condition?

      ea0034p426
    • Renal function in goitrous patients attending endocrinology clinic in a South Western Nigerian hospital

      ea0034p427
    • The influence of thyrotoxicosis on circulating cortisol and response to Synacthen

      ea0034p428
    • Frequency of biochemical thyroid dysfunction in hospitalised patients: analysis of 280 000 admissions to a large centre

      ea0034p429
    • Pre-operative cytology vs post-operative histology in thyroid nodules

      ea0034p430