Endocrine Abstracts

For almost three decades, my group and I have been studying the functions of known proteins and deciphering the roles of novel genes and small RNAs expressed within the reproductive axis. Many of these studies have focused on the glycoprotein hormones as well as members of the transforming growth factor β superfamily. We have also used multiple strategies to identify unique germ-cell expressed genes and probed their essential roles in knockout mouse models. These studies have led us to an understanding of the intricate pathways required for development and function of the reproductive axis in mammals.