Endocrine Abstracts

The aim of this study was to determine the structure of the primary incidence of hyperprolactinemia among the female population of the city during 2011. 114 medical cards of women with hyperprolactinemia were researched and analyzed. It was determined that the mean age of the case detection was 28.9 years (σ=8.2). The main clinical features were the disturbances of menstrual period (41.2%), infertility (26.3%), galactorrhea (21.9%) and the changes of the body weight (7.9%). Among the disturbances of menstrual period were amenorrhea (40%) and irregular menstruation (60%). The majority (73%) of women with infertility have no any other clinical features. By the end of 2011 the pituitary MRI scan was performed in 81 women with hyperprolactinemia. The results of the pituitary MRI showed that 72% (58) of women with hyperprolactinemia had microadenomas, 6% (5) had probable signs of microadenomas, 22% (18) had no signs of microadenoma. 63% (20) of hyperprolactinemic women with the disturbances of menstrual period had microadenomas, 9% (3) had probable signs of microadenomas, 28% (9) had no signs of microadenoma. 72% (18) of infertile women with hyperprolactinemia had microadenomas, 4% (1) had probable signs of microadenomas, 24% (9) had no signs of microadenoma. 100% (17) hyperprolactinemic women with galactorrhea had microadenomas.

The results show that it’s necessary to test a serum prolactin of infertile women. The pituitary MRI in hyperprolactinemic women is recommended to diagnose a microadenoma.