Endocrine Abstracts

Aim: The aim of this study is evaluating of body composition and frequency of sarcopenia in women depending on age.

Materials and methods: We’ve examined 8637 women aged 20–89 years (mean age – 56.7±0.14 years; mean height – 162.5±0.07 cm; mean weight – 73.5±0.16 kg). The patients were divided into two groups depending on age: 20–24 (n=143), 25–29 (n=209), 30–34 (n=271), 35–39 (n=326), 40–44 (n=419), 45–49 (n=794), 50–54 (n=1292), 55–59 (n=1534), 60–64 (n=1193), 65–69 (n=943), 70–74 (n=877), 75–79 (n=384), 80–84 (n=204) and 85–89 years (n=48). Lean and fat masses and total body, lumbar spine, femoral neck bone, forearm bone mineral density (BMD) were measured by DXA using a densitometer Prodigy, GE.

Results: We have found the significantly differences of fat and lean masses in women with age:

– fat mass: 20–24 years – 18 630.12 g; 25–29 years – 18 630.12 g; 30–34 years – 19 201.00 g; 35–39 years – 21 528.15 g; 40–44 years – 24 611.77 g; 45–49 years – 2750.54 g; 50–54 years – 27 501.54 g; 55–59 years – 29 909.92 g; 60–64 years – 31 600.27 g; 65–69 years – 33 508.25 g; 70–74 years – 33 155.54 g; 75–79 years – 32 284.86 g; 80–84 years – 30 595.53 g; 85–89 years – 30 303.68 g; F=83.19; P<0.0000001;

– lean mass: 20–24 years – 37 271.57 g; 25–29 years – 37 954.09 g; 30–34 years – 39 019.72 g; 35–39 years – 39 928.62 g; 40–44 years – 40 929.67 g; 45–49 years – 41 407.19 g; 50–54 years – 41 936.27 g; 55–59 years – 42 564.79 g; 60–64 years – 42 519.73 g; 65–69 years – 41 758.95 g; 70–74 years – 41 233.77 g; 75–79 years – 41 105.52 g; 80–84 years – 40 308.00 g; 85–89 years – 38 454.61 g; F=29.15; P<0.0000001.

Frequency of sarcopenia in women aged 65 years and older was 7% (women aged 65–69 years (n=943) – 7.6% (n=72), 70–74 years (n=877) – 6.1% (n=54), 75–79 years (n=384) – 6.3% (n=24), 80–84 years (n=204) – 6.9% (n=14), 85–59 years (n=48) – 10.4% (n=5).

Conclusion: Fat and lean masses were significantly decreased with age. The maximal accumulation of fat and lean masses was in women aged 50–59 years. Frequency of sarcopenia in women aged 65 years and older was 7%.