Endocrine Abstracts

Introduction: Cushing’s syndrome is rare but severe because of his association with multiple complications and particularly increased cardiovascular factors. This complications determine a mortality rate four times higher than in general population.

Objects: The aim of our study was to evalated the prevalence of cardiovascular factors in Cushing’ syndrome.

Subjects and methods: Twenty-five patients with Cushing’ syndrome were retrospectively evaluated from 2008 to 2011. All of them were evaluated for anthropometric (weight, height, waist circumference, biochemical profile (including fasting glucose and oral glucose tolerance test, lipids), and clinical blood pressure.

Results: The mean age was 35.6 years, and the sex ratio 4/1 (females/males).

86% of the patients were overweight and 57.3% had high waist circumference. 76.3% of the patients had hypertension, 69.5% had impaired glucose tolerance or diabetes, 48% had hypoHDLemia and 35.2% had hypertriglyceridemia.

Conclusion: Control of all cardiovascular risk factors should be one of the primary goals during the follow-up of these patients as remission from hypercortisolism is difficult to achieve and cardiovascular risk can persist even after remission.