Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2013) 32 P374 | DOI: 10.1530/endoabs.32.P374

1Baskent University Istanbul Hospital, Istanbul, Turkey; 2Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey.


Introduction: The total energy expenditure in pregnancy is increased largely due to elevated basal metabolic rate (BMR) during pregnancy. The aim of this study is to evaluate the effects of gestational diabetes on basal metabolic rate, body weight and HbAlc, by comparing these parameters in gestational diabetic and healthy pregnant women.

Method: Fifty-eight gestational diabetic women (GDM) and fourty healthy non diabetic pregnants who had normal thyroid function and not taking any medication which may possibly alter the metabolic rate, recruited in the study. Mean ages of the study population were 21–42 years. GDM was diagnosed by a 100 g-OGTT after 50 g oral glucose challenge test. Basal metabolic rate was measured by oxygen consumption after 8 h overnight fasting, also BMI, fasting blood glucose (FBG) and HbA1C were measured in gestational weeks of 24–32. Due to body weight gain as expected during pregnancy, BMR was divided by BMI to ensure normalization.

Results: The rate of BMR to BMI was found 50.30±10.58 kcal/day in GDM group and 51.98±9.70 kcal/day in non-GDM group. The difference was not statistically significant. FBG and HbA1c were higher in GDM women as expected. No statistically significant relationship was found either between BMR and FBG and HbA1c levels and body weight.

Discussion: In our study, the average BMR was not different in GDM women compared to pregnants who do not have gestational diabetics. These results might be different in the third trimester of pregnancy instead of second trimester.

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