Secondary hypertension and hirsutism as a clinical manifestation of the tumor duplicity: case report

Zdenek Frysak; David Karasek; Igor Hartmann; Ladislava Kucerova

doi:10.1530/endoabs.32.P266

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Endocrine Abstracts (2013) 32 P266 | DOI: 10.1530/endoabs.32.P266

ECE2013 Poster Presentations Clinical case reports – Pituitary/Adrenal (57 abstracts)

Secondary hypertension and hirsutism as a clinical manifestation of the tumor duplicity: case report

Zdenek Frysak ¹ , David Karasek ¹ , Igor Hartmann ² & Ladislava Kucerova ³

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¹Department of Internal Medicine III – Nephrology, Rheumatology and Endocrinology, Faculty of Medicine and Dentistry, University Hospital of Olomouc, Olomouc, Czech Republic; ²Department of Urology, Faculty of Medicine and Dentistry, University Hospital of Olomouc, Olomouc, Czech Republic; ³Department of Clinical and Molecular Pathology, Faculty of Medicine and Dentistry, University Hospital of Olomouc, Olomouc, Czech Republic.

Differential diagnostic search for the pathogenetic causes of hirsutism and the combination of hypertension can provide very interesting results for the clinicians. The case report demonstrates a patient suffering from two hormonally active tumors – adrenal adenoma with primary aldosteronism and primary Leydig cell ovarian tumor with hyperandrogenism. The task of the authors was easier due to the perimenopausal age of the proband. Selective venous sampling was very helpful in diagnosis of these endocrine active tumors. Both of them were resolved by a single laparoscopic surgery. The combination of the two described tumors is the really unique clinical finding. The solution using laparoscopy in a single procedure provided an elegant and efficient therapeutic approach.