Endocrine Abstracts

The improvement of physical function and mobility in a continuously expanding elderly population emerges as high priority of medicine today. Muscle mass, strength and maximal exercise capacity are major determinant of physical function and all have been shown to decline with aging which may contribute to the increase incidence of frailty and disability observed in elderly men whereas the decline in exercise capacity may facilitate the accumulation of body fat and insulin resis...

Osteoporosis is a silent disorder characterized by reduced bone strength predisposing to increased fracture risk. Although osteoporosis affects women more often than men, ~20% of the 44 million Americans who have osteoporosis or low BMD are men. Between 30 and 40% of fractures due to osteoporosis occur in men; the lifetime risk of fracture for men aged 50 or older is between 13 and 30%. Osteoporosis in men causes significant morbidity and mortality. The major mechanism underly...

Introduction: This is a review of cognitive decline in male ageing.Methods: Literature review and analysis of cognitive data from the Healthy Old People of Edinburgh (born 1905–1919), Lothian Birth Cohort 1921 and Lothian Birth Cohort 1936 studies.Results: Cognitive scores in men increased relative to those of women between childhood and late adulthood, but changes in old age were little affected by sex once other factors, suc...