ECE2013 Poster Presentations Diabetes (151 abstracts)
Evaluation of BICI therapy in pregestational type 1 diabetes
Pilar Roldan , Isabel Mateo , Jose Ortego , Gloria Baena , Laura Larran , Inmaculada Gavilan , Belen Ojeda , Julian Tamayo & Manuel Aguilar-Diosdado
H.U. Puerta Del Mar, Cadiz, Spain.
Objective: To evaluate in our area BICI therapy efficacy in pregestational type 1 diabetes.
Methods: We conducted a descriptive retrospective analysis studying metabolic control and obstetrics results in patients with pregestational type 1 diabetes, treated with BICI between 2004 and 2012 in our hospital.
Results: We evaluated 28 patients with type 1 diabetes and diabetes duration of 17.3±6.6 years. In 27.3% of patients the treatment with BICI was indicated for reasons other than prenancy. Of the remaining, 18.7% performed treatment with BICI planning pregnancy, and in 81.3% started this therapy for bad metabolic control during the pregnancy, despite intensive insuline therapy. Only 39.3% of pregnancies were planned. Women had no ketoacidosis or severe hypoglycemia. Regarding the onset and progression of chronic complications, only in one patient was detected progression of diabetic retinopathy. The completion of gestation was 34.2±5.4 weeks and was performed by planned cesarean in 28.6%, urgent cesarean in 25% and vaginal delivery in 14.3% of the cases. Two patients had spontaneous abortion. There were no others perinatal complications, presenting fetal macrosomia 31.25% of newborns.
Conclusions: BICI therapy represents a safe and effective strategy to optimize metabolic control in patients with pregestational type 1 diabetes poorly controlled with conventional intensive insulin treatment, to plan pregnancy or to achieve good metabolic control in the case of unplanned pregnancies.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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