Endocrine Abstracts

Objective: Relationship between pre-pregnancy BMI (PPBMI) in gestational diabetic (GD) patients, and age, country of origin, family history of type 2 diabetes mellitus (T2DM), GD history, and BMI after pregnancy.

Methods: Transversal, descriptive study of 259 consecutive pregnant with confirmed DG. Analysis were based on Fisher’s exact test and Student’s t-test. A P<0.05 was significant (SPSS 19.0).

Results: Mean age was 34.3 years, 49.8% primiparous, 66.7% Spanish, 17.4% South American, 5.5% Eastern European, 3.1% North African, 2.0% South Africans, 3.5% Chinese, 0.8% Indian, and 0.4% Portuguese/Cuban. Women with a family history of T2DM had a mean average of 2.51 kg/m² PPBMI higher than pregnant without such a history (P<0.001). The mean PPBMI was 27.1 kg/m² (30% overweight and 28.0% obese). Thirty-three percent of Spanish pregnant were overweight and 25.4% obese, vs 22.6 and 33.3% respectively amongst the other countries. A positive correlation was observed between age and PPBMI (P=0.012). There was a statistically significant difference for the PPBMI of the primiparous compared to the multiparous, with a mean difference of 2.4 kg/m² in favour of the latter. Postpartum mean BMI between, 4 and 6 months after delivery was 27.2 kg/m² showing no significant difference to the PPBMI.

Conclusions: Is interesting the high average age of the pregnant, the high percentage of overweight and obese women before pregnancy and the positive correlation of PPBMI and age in all pregnant. However PPBMI is higher in multiparous and was positively correlated with family history of T2DM. The data observed in the study population suggest the possibility of an increase in the development of T2DM in these patients, so it will be advisable to tighter control of the same.