Endocrine Abstracts

Introduction: Vitamin D (Vit D) is known for its action on bone metabolism. But recently more ubiquitous actions have been discovered. Vit D deficit is now considered as a world health problem because of it frequency and its consequences. Vit D deficiency seems to be involved in diabetes mellitus, and in autoimmune, neoplastic and cardio-metabolic diseases. The aim of our study was to analyze the incidence of cardio-metabolic diseases in a group of patients with vitamin D deficiency.

Subjects and methods: This retrospective study analyzed 23 patients with vitamin D deficiency (25OH vit D levels <30 ng/ml) diagnosed during the exploration of normocalcemic hyperparathyroidism.

Results: Mean age was equal to 57.5±11 years. The mean BMI=30.8±7.21 kg/m². A BMI ≥25 kg/m² was found in 87% of our patients (56% were obese and 31% were overweighed). Systemic high blood pressure was observed in 34.7%. 21.7% were dyslipidemic and 21.4% had glucose metabolism disorders.

Conclusion: In this study, although our subjects are relatively young, they are at high risk for cardio-metabolic diseases especially for obesity. But, as obesity interact on vitamin D deficiency; it is difficult to say which is the most deleterious for cardiovascular diseases. So, in future, prospective and large series with multivariate analyses are needed to confirm our results.