Endocrine Abstracts

The activity of the renin–angiotensin system (RAAS) is elevated in the circulation and in various tissues and organ tissues. The increased RAAS activity plays an important role in the haemodynamic and non-haemodynamic pathogenetic mechanisms involved in kidney and vascular (CV) disease. Previous studies have demonstrated that albuminuria is not only a marker of glomerular lesions but also a progression promoter and finally a powerful predictor of the long term beneficial ...