Endocrine Abstracts

We look into total 67 patients with non-functioning pituitary adenoma and review their bone mineral density in association with age and gender, effect of radiotherapy and hormonal replacement.

Age range: 5.97% (4 patients) are between 18 and 40 years, 43.28% (29 patient) between 41 and 60 years and 50.74% (34 patients) are between 61 and 86 years.

Gender: 61.19% (41 patients) are male and 38.8% (26 patients) are female.

Radiotherapy: 59.7% (40 patients) received Radiotherapy. Among them 70% (28 patients) had normal BMD, 22.5% (9 patients) had osteopenia and 7.5% (3 patients) had osteoporosis.

16.41% (11 patients) developed osteopenia and 1.49% (1 patients) had osteoporosis even without radiotherapy.

Treatment: 29.85% (20 patients) received growth hormones. Among them 19.4% (13 patients) had normal BMD, 8.95% (6 patients) had osteopenia and 1.49% (1 patients) had osteoporosis 50.74% (34 out of 67) received sex hormone replacement. Among them, 32.83% (22 patients) had normal BMD, 16.41% (11 patients) had osteopenia and 1.49% (1 patients) had osteoporosis.

8.95% (6 patients) needed vitamin D supplement. Among them 5.97% (4 patients) had normal BMD and only 2.98% (2 patients) had osteopenia.

61.19% (41 patients) were taking hydrocortisone. Among them, 29.85% (20 patients) had normal BMD, 23.88% (16 patients) developed osteopenia and 5.97% (4 patients) had osteoporosis.

Conclusion: Majority of the patients are in the age range of 61–86 years and most of them are male. Radiotherapy, hormonal deficiencies or hormonal replacement did not influence outcome of BMD.

8.95% (6 patients) needed vitamin D supplement. Among them 5.97% (4 patients) had normal BMD and only 2.98% (2 patients) had osteopenia.

61.19% (41 patients) were taking hydrocortisone. Among them, 29.85% (20 patients) had normal BMD, 23.88% (16 patients) developed osteopenia and 5.97% (4 patients) had osteoporosis.

Conclusion: Majority of the patients are in the age range of 61–86 years and most of them are male. Radiotherapy, hormonal deficiencies or hormonal replacement did not influence outcome of BMD.