Endocrine Abstracts

Introduction: Diabetes mellitus is considered a cardiovascular risk equivalent. The presence of other cardiovascular risk factors in patients with diabetes may imply synergy for the occurrence and severity of cardiovascular morbidities and mortalities. Metabolic syndrome is the presence of these clusters of cardiovascular risks in an individual. Metabolic syndrome has been shown to be associated with some traditional risk factors and emerging risk factors.

Aim: This study determined the prevalence of metabolic syndrome defined by the International Diabetes Federation (IDF) in people with type 2 diabetes mellitus, and also determined its associations.

Method: A case–control study involving 150 Nigerians with Diabetes and 150 age and sex matched controls. Relevant clinical and anthropometric measurements were taken and laboratory investigations were done. Statistical analysis was done using SPSS 14. Regression analysis was done to determine the factors associated with Metabolic Syndrome and regression results were interpreted using odds ratio and confidence intervals.

Results: The mean±S.D. age of the diabetic and control groups were 56.12 (±7.65) years and 55.76 (±7.49) years respectively (P=0.681). Prevalence of metabolic syndrome among diabetics and control were 68.7 and 14.7% respectively. Female gender, hypertension, and abdominal obesity were associated with increased odds for metabolic syndrome.

Conclusion: Metabolic syndrome is common among our diabetic patients. Detection and management of its cluster of risks may be an essential component in reducing its occurrence.