ea0031pl2 | Society for Endocrinology Hoffenberg International Medal Lecture | SFEBES2013
Labrie Fernand
Man is unique, with some other primates, in having adrenals that secrete large amounts of dehydroepiandrosterone (DHEA). The problem with DHEA, however, especially for women, is that its secretion from the adrenals starts decreasing at the age of 30 years and has already declined, on average, by 60% at menopause. Since there is no other source of sex steroids after menopause than those made locally in peripheral tissues by the mechanisms of intracrinology, it is logical to bel...