ICEECE2012 Poster Presentations Endocrine Disruptors (26 abstracts)
The Interference Endocrinous – Metabolic in Thyro-gonadal Failure
M. Bistriceanu 1 , M. Popescu 1 , I. Bistriceanu 2 , S. Preda 1 , S. Bondari 1 , D. Bondari 3 , A. Covei 3 & M. Preda 2
Hospital Philanthropy, Craiova, Romania.
It is known that the genetic similarity, embryonic and functional hypothalamic-pituitary-gonadal system has close correlation with hypothalamic-pituitary-thyroid axis. Recent research has suggested the existence of interactions between the gonad and the functional capacity of the thyroid.
The study was performed on 93 cases admitted to the Endocrinology Clinic during 2005–2011, whose age ranged from 16–44 years. Correlate with clinical features Thyro-gonadal function exploration objectified by hormonal and metabolic laboratory investigations performed in the context of specific clinical case. Note that all cases included in the study had an extra weight in varying degrees.
Hormonal assays results obtained by us show that overweight patients studied, ovary and thyroid functional capacity are significantly reduced. Reduced urinary excretion of estrogen, along with decreases in serum thyroid hormones, explaining increased serum cholesterol and β-lipoproteins and decreased progesterone involves a gradual increase serum lipids.
Conclusion: In view of relations between endocrinology and gynecology, comprehensive approach is required to study endocrino-metabolic correlation in thyro-ovarian failure, to adopt a differentiated therapeutic attitudes pathogens.
Declaration of interest: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.
Funding: This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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