Endocrine Abstracts

Introduction: Aim is to determine vitamin D level in patients with Type 2 DM and to evaluate the relationship between vitamin D level and glycemic control.

Methods: We evaluated 107 women and 63 male patients with Type 2 DM whose mean age was 55±0.81. Patients fasting blood glucose (FBG), postprandial blood glucose (PPBG), HbA1c and 25(OH)D3 level were measured. The cases were divided into three groups according to measured 25(OH)D3 level (Vitamin D value ≤20 ng/ml, between 20–30 ng/ml, ≧30 ng/ml). DM less than 6 months duration, hypercalcemia or hypocalcemia, existing diagnoses of hyperparathyroidism or hypoparathyroidism, receving vitamin D treatment were excluded.

Results: Vitamin D level was found ≤20 ng/ml in 41 cases, between 20–30 ng/ml in 50 cases and ≧30 ng/ml in 79 cases. Mean 25(OH)D3 level was found as 38.10 ng/ml (11 to 68.7 ng/ml) in men and 24.20 ng/ml (5.8 to 70.7 ng/ml) in female (P:0.001). Between the vitamin D groups, no significant difference was founding in terms of the FBG, PPBG and HbA1c levels (P:0.97, 0.96, 0.44). Between the vitamin D groups, in regard to age, BMI and waist circumference, significant differences were detected (P<0.001). There was a significant difference between calcium (Ca) levels between these 3 groups (P: 0.02). Vitamin D level was higher in the group with HbA1c ≤7 than the group with HbA1c> 7 (P: 0.115).

Conclusion: A53% of the patients with Type 2 DM was found to have vitamin D deficiency and insufficiency. Vitamin D deficiency was more evident in women than in men. Although there was not any difference in terms of blood glucose regulations between the patients with Vitamin D deficiency or insufficiency and without deficiency, vitamin D level was found to be higher in patients with HbA1c≤7.

Declaration of interest: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.

Funding: This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.