Endocrine Abstracts

Introduction: The association between type 2 diabetes mellitus and obesity is very close. Obesity is common in women aged between 45 and 49 years. Prevalence of prediabetes, i.e. impaired fasting glucose also seems to be higher in women than men in the Indian population. The present work is planned to study the prediabetic status in preobese and obese in pre- and post-menopausal women with the help of estimation of fasting blood glucose (FBG) levels.

Materials and method: Fasting blood glucose levels and BMI were estimated in 300 asymptomatic women with no family history of type 2 diabetes mellitus (DM) using GOD–POD method. Pre- and post-menopausal subjects are divided in control (I), preobese (IIa) and obese group (IIb). The results is analyzed statistically ANOVA test.

Result and conclusion: Mean FBG levels in preobese and obese group are higher than control group in both pre- and post-menopausal women. There is significant difference between BMI and fasting blood glucose levels in pre- and post-menopausal women. In a nutshell obesity with & without menopause both act as a important predictor for type 2 DM. Thus in premenopausal women lifestyle modifications may prove as important means for prevention of obesity and type 2 DM to minimize the complication in post-menopausal status.

Declaration of interest: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.

Funding: This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.