Endocrine Abstracts

Background: Diabetes mellitus is the most common endocrine metabolic disorder of childhood. It is widely spread all over Egypt as its prevalence was found to be 1.09 per 1000 among school aged children.

Aim of the work: The aim of this work was to do a retrospective epidemiological study of the records of diabetic children attended the outpatient pediatric clinic in NIDE.

Subjects & Methods: The files 0f 3000 diabetic children were examined retrospectively without any reference to the personal data.

Results: The results showed that there is no statistical differences between male, (n=1528) to female, (n=1472) distribution. The results of this retrospective study showed that the mean age of onset of diabetes in children attended the outpatient pediatric clinic of National Institute of Diabetes was (mean =8.37+10.96 y). The present study showed also that there was a decrease of age of onset of diabetes among diabetic children as the age of onset between 5–<10 years were the highest percentage (46%). As regards the insulin regimen used by the diabetic children, 17.5% used conventional insulin therapy, 11% used modified insulin therapy as they used regular insulin before lunch, and 71.5% used basal-bolus insulin regimen. The mean percentage of insulin unites per Kg. was 1.00+0.38 U/kg./day. The mean BMI was=24.54+6.42, while the BMI distribution was: 56% were with normal weight=< 25, 27% were overweight=25: <30, 14% were obese=30: < 40 and only 3% were with severe obesity where BMI=> 40. The results showed also that 34.8% of the diabetic patients were doing continues home blood glucose monitoring with glucose sensors, 25.8% were doing the monitoring only with visual strips, while 39.4% of the diabetic children were not doing home monitoring at all.

Conclusion & recommendations: The discussion of these results documented that it will be essential to follow the international guidelines of management of type 1 diabetes and it was recommended to do proper diagnosis of different types of diabetes among diabetic children and to study the prevalence and incidence of diabetes among Egyptian children as the prevalence and incidence still uncertain till now.

Declaration of interest: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.

Funding: This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.