ICEECE2012 Poster Presentations Thyroid (non-cancer) (188 abstracts)
Hyperthyroidism and Pregnancy
M. Amani 1 , F. Chentli 2 , S. Amani 3 , N. Midoun 1 , N. Benfeghoul 4 , A. Rih 4 , L. Zemour 1 & N. Boumansour 1
1EHU 1st November 1954, Oran, Algeria; 2CHU Bab-el-oued, Algiers, Algeria; 3CHU Benzerdjeb, Oran, Algeria; 4Djilali Liabes university, Sidi-bel-abbès, Algeria.
Introduction: Hyperthyroidism affects 2 to 3% of pregnant women. The prevalence of clinical hyperthyroidism during pregnancy is variously appreciated. Hyperthyroidism prior to pregnancy is probably more common than in connection with the gestationnal state as gestational hyperthyroidism usually blocks fertility. Our objectives are the prevalence and the causes of hyperthyroidism in pregnant women in the 1st quarter.
Description of methods: Prospective study, made in Oran area, on 270 pregnant women in 1st quarter. Women who smoke (active smoking confessed) and those followed for thyroid disease or taking medications that interfere with the thyroid gland were excluded.
-Study protocol: clinical examination, thyroid stimulating hormone, free thyroxine, free triiodothyronine, thyroid antibodies (anti-TPO, anti-thyroglobulin and TSI) and cervical ultrasonography.
- Statistics tests: collection of data on EPI INFO 5.1, bivariate analysis (the chi-squared test, the Pearson chi-squared test, the Yates corrected chi-squared test, the Wilcoxon chi-squared test (Log rank sum) or Mann-Whitney, the variance analysis method (ANOVA), the r correlation test, significance level P<0.05, multivariate analysis (SPSS: 10 version and MedCalc).
Results: −2/270 Pregnant women in 1st quarter (0.7%) had hyperthyroidism.
-The etiology of thyrotoxicosis was related to gestational transient hyperthyroidism.
- No case of Graves’ disease was found.
Conclusion: Hyperthyroidism is a rare disorder during pregnancy but the consequences are serious for both mother and offspring.
Declaration of interest: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.
Funding: This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector
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