Endocrine Abstracts

Patient in the case, an 18-year-old male, complained of constant tiredness, frequent malaise, day time sleepiness, epigastric pain, poor appetite and consumption of great quantity of water. These conditions had persisted for 3–4 years. He had gone to many different physicians, with different tests taken, but without diagnose. Upon physical examination, the pale skin, scanty of pubic hair, and no presence of beard and axillary hair raised the possibility of Panhypopituitarism. This suspicion was reinforced by the result of blood examination which showed normocytic anemia, hypokalemia (K: 3.27 mg/dl), secondary adrenal insufficiency, secondary hypothyroidism and secondary hypogonadism. With further examination, the Pituitary stimulation test showed poor response. Water deprivation test indicated severe central diabetes insipidus. Bone density was relatively low (Z-score: −2.3). The result of pituitary MRI showed a soft tissue lesion in the pituitary stalk with heterogeneous enhancement.

Declaration of interest: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.

Funding: This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.