Endocrine Abstracts

Aim: To evaluate dermatologic findings in diabetic and nondiabetic acromegalic patients and compare with nonacromegalic diabetic patients. Also to investigate any possible correlation between skin lesions and colonic and thyroid neoplasms.

Materials and methods: Data from dermatologic examination of 32 acromegalic and diabetic nonacromegalic patients were compared. Colonoscopic, ultrasonographic and biochemical findings of acromegalic patients were evaluated for any correlation.

Results: Twenty nondiabetic and 12 diabetic acromegalic patients had similar number of skin tags compared to each other and to 21 nonacromegalic diabetic patients. Only IGF1 levels were correlated with the presence and number of skin tags and colonic polyps. Insulin levels were correlated with the presence of colonic polyps and thyroid nodules but not correlated with skin tags. The presence of skin tags was significantly correlated with colonic polyps but not correlated with thyroid nodules.

Conclusion: In our study group, IGF1 and not insulin levels affected the formation of skin tags. Skin tags could be a marker of colonic polyps, but are not related to thyroid nodules.

Declaration of interest: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.

Funding: This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.