ICEECE2012 Poster Presentations Male Reproduction (63 abstracts)
Subcutaneous gonadotropin therapy for male infertility by hypogonadotropic hypogonadism
P. Moreno , M. Gálvez Moreno , M. Alhambra Expósito , I. Prior Sánchez , C. Muñoz Jimenez , R. Palomares Ortega & P. Benito López
Hospital Universitario Reina Sofía, Córdoba, Spain.
Objetive: Evaluate the efficacy of subcutaneous HCG with or without FSH in male infertility associated to hypogonadotropic hypogonadism (HH).
Patients and methods: Descriptive study of patients with HH treated with HCG s.c. with or without FSH, for fertility objective (2004–2011). The Treatment was initiated with HCG 500 UI/72 h s.c., periodic monitoring of testosterone and semen analysis was realized, adjusting doses up to 2500 UI/72 h. If no answer obtained after 1 year, combined treatment with FSH s.c. was started. Analyzed data: cause of HH, age, testosterone levels, semen, dose of HCG and FSH treatment. The result has been assessed to the achievement of pregnancy.
Results: Ten patients. 30.6±2.9 years old. Cause of HH: 50% idiopathic, 20% nonfunctioning pituitary adenoma, 10% prolactinoma, 10% acromegaly and 10% craniopharyngioma. Fertility 60%, 22.6±13.5 months treatment time. Only one patient discontinued treatment without success. No presence of side effects. Subgroup result:
Conclusions: Subcutaneous gonadotropin therapy is effective in infertility HH. Treatment with subcuataneous HCG alone is successful. No presence of side effects.
Declaration of interest: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.
Funding: This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.
| Less than 24 months (n=6) | More than 24 months (n=4) | |
| Patients (%) | 60 | 40 |
| Doses HCG (UI/72 h) | 1250±612.4 | 2125±750 |
| FSH (%) | 30 | 50 |
| Testosterone (mcg/l) | 7.6±3.9 | 7.3±5.5 |
| Time (months) | 13.2±7.5 | 36.7±3.4 |
| Fertility (%) | 50 | 75 |
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more