Endocrine Abstracts

One of the most clinical characteristic of Turner’s syndrome is the final short stature.

In order to cure this handicap, several teams were interested to treat these patients by the GH.

We report two cases of Turner syndrome associated with GH deficiency.

In the first, a 17 years old girl, having a delayed growth lower than −4 S.D. associated with delayed puberty and dysmorphic syndrome. A karyotype made confirmed the diagnosis of Turner’s syndrome. In front of the short stature lower than that usually found in the Turner syndrome, GH was measured during insulin induced hypoglycaemia test and L-dopa test. The two tests revealed a GH deficiency.

The second observation is about a 21 years old girl having a delayed growth between −2 and −3 S.D. associated with delayed puberty and dysmorphic syndrome.

The karyotype finds a chromosomal formula with 45×0 confirming the Turner’s syndrome.

GH was measured under stimulation test, showing a GH deficiency.

The dosage of the GH in Turner’s syndrome appears interesting and must be of current practice especially when the short stature is lower than that usually found in Turner syndrome.

Declaration of interest: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.

Funding: This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.