ICEECE2012 Poster Presentations Thyroid (non-cancer) (188 abstracts)
Hyperglycaemia in hyperthyroidism predictive factors
S. Azzoug 1 , D. Remini 2 , S. Fellah 2 , E. Koceir 2 & F. Chentli 1
1Bab El Oued Hospital, Algiers, Algeria; 2Bab Ezzouar University, Algiers, Algeria.
Glucose abnormalities are frequent in hyperthyroidism; the aim of our study is to determine the predisposing factors of glucose disturbances in hyperthyroidism.
Subjects and methods: It is a retro and prospective study including 263 hyperthyroid subjects, patients having fasting glycaemia <1 g/l and/or glycaemia after OGTT <1.40 g/l (G1) were compared to patients having fasting glycaemia ≥1 g/l and/or glycaemia after OGTT ≥1.40 g/l (G2).
Results: Seventy-five patients (G2) had glucose abnormalities. Patients of G2 were older than those of G1, underlying hypertension and familial diabetes were more prevalent in G2. There was no difference between the two groups for the other factors studied (Table 1).
Discussion and conclusion: Ageing, underlying hypertension and familial diabetes are risk factors for glucose abnormalities in hyperthyroid subjects whereas the severity of hyperthyroidism is not which suggest that hyperthyroidism may worsen glucose metabolism in patients at risk of type 2 diabetes.
Declaration of interest: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.
Funding: This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.
| G1 | G2 | P | |
| Number (%) | 188 (71.48%) | 75 (28.52%) | |
| Family Diabetes (%) | 31.38% | 48% | <0.05 |
| Hypertension (%) | 6.91% | 25.33% | <0.05 |
| Age (years) | 40.07±1.22 | 49.27±1.96 | <0.01 |
| BMI (kg/m2) | 22.94±0.33 | 24.05±0.67 | NS |
| FT4 (pmol/l) | 43.55±2.43 | 32.62±3.51 | NS |
| FT3 (pmol/l) | 19.88±1.47 | 16.24±2.05 | NS |
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