ICEECE2012 Poster Presentations Thyroid (non-cancer) (188 abstracts)
Elastography in the differential diagnosis of thyroid nodules
E. Çakal 1 , M. Sahin 1, , I. Öztürk Ünsal 1 , A. Güngünes 1 , E. Tutal Akkaymak 1 , E. Çakir Özkaya 1 , N. Çolak Bozkurt 1 , M. Özbek 1 & T. Delibasi 1
1Ankara Diskapi Training and Research Hospital, Ankara, Turkey; 2Ankara University School of Medicine, Ankara, Turkey.
Objective: Despite the publication of a recent meta-analysis of elastography in thyroid nodules, further work is necessary on this issue in different populations. In this study we aimed to evaluate the clinical value of elastography in nodular goiter in mild iodine defficient region without excluding according to nodule charecteristics.
Materials and methods: This prospective study was conducted between April 2010 and December 2011 in Yildirim Beyazit Diskapi Research Hospital Endocrinology outpatient clinic. Five hundred and twenty eight nodular goiter patients underwent included whom thyroid fine-needle aspiration biopsy (FNAB) were included in our study.
Results: There were 471 females and 57 males and their age ranged from 45 to 78 years. Total 586 nodules were evaluated in these patients. Elastography score and index were measured with real time ultrasound elastography (Hitachi EUB 7000 HV machine with using 13 MHz linear transducer). The area under the curve (AUC) for the elasto score (AUC) was 0.90 (P<0.0001) and AUC for the strain index was 0.945 (P<0.0001). We suggest that strain index reflects malignancy better than the elasto score. We conclude that 3.5 (68% sensitivity and 99% specifity) is cut-off point for elasto score. For strain index we conclude that 3.9 (73% sensitivity and 99% specifity) is cut-off point.
Conclusion: Strain ratio and strain index measurements of thyroid nodules in our population is efficient and increase the diagnostic performance of the sonography.
Declaration of interest: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.
Funding: This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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