ICEECE2012 Poster Presentations Thyroid cancer (108 abstracts)
Surgery of Papillary Thyroid Carcinoma in Children and Adolescents
R. Dzodic 1, , I. Markovic 1, , I. Djurisic 2 , M. Buta 2 , M. Oruci 2 , M. Jevric 2 , G. Pupic 2 & Z. Milovanovic 2
Institute of Oncology and Radiology of Serbia, Belgrade, Serbia.
Background: Papillary thyroid carcinoma in children and adolescents is rare but it shows extremely aggressive behavior. Gross lymph node metastases and distant metastases are common on first clinical presentation.
Patients and methods: Forty five children and adolescents were operated due to PTC. Mean age was 16.6 years (range 7–21). At the time of diagnosis 13% had lung metastases. Total thyroidectomy or completion of thyroidectomy was performed in all cases followed with central neck dissection and frozen section examination of lower jugulo-carotid compartments
Results: Median tumor size was 1.9 cm. PTC was found in 44 and FTC in one patient. Multifocal tumors were found in 37% and capsular invasion in 29% and vascular invasion in 24% of cases. LNM in either central or lateral neck compartments were found in 76% of patients. Capsular and vascular invasion were significantly more frequent in children less than 16 years of age. Median follow-up was 127 months. Overall survival rate was 100%.
Conclusion: PTC in children is characterized with high incidence of loco-regional aggressiveness, multifocality, lymph node metastases and distant metastases at the time of diagnosis. Extensive surgical approach should be performed in both primary and recurrent disease in young patients with PTC.
Declaration of interest: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.
Funding: This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more