Endocrine Abstracts

Introduction: Infiltration of larynx by thyroid cancer represents fourth stage of the disease and is threatening disease. Lethal outcome of advanced thyroid cancer, which invades trachea and larynx, is usually associated with airway obstruction.

Patient and method: We are presenting 58 year old woman operated due to the advanced papillary carcinoma Patient underwent total thyroidectomy, central neck dissection, modified radical dissection of the right side, selective dissection on the left side, auto-transplantation of left parathyroid gland, partial vertical laryngectomy and reconstruction of defects with epiglottis and surgical tracheotomy. After surgical treatment she received a dose of 5.5 GBq J 131st. Postoperative stenosis of the larynx was treated twice with laser surgery.

Results: Traheostomy has been closed and the phonatory and respiratory functions were preserved after treatment. One year of follow up has passed with no signs of relapse.

Conclusion: Decision of resectability of the tumor with reconstruction of the defect in the larynx is the most commonly intraoperative decision. Radical surgery is a logical and rational therapeutic approach for thyroid cancer in the fourth stage.

The goal of radical surgery in locally advanced thyroid cancer is to prevent lethal outcome but can also be curative form of therapy with good quality of life.

Declaration of interest: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.

Funding: This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.