ICEECE2012 Poster Presentations Obesity (114 abstracts)
Factors determining weight gain in adults and relation with glucose tolerance
F. Soriguer 1, , G. Rojo-Martinez 1, , S. Valdes 1, , M. Tapias 1 , P. Botas 3 , E. Delgado 4 , I. Esteva 1, , M. Ruiz de Adana 1, , F. Diaz-Cadorniga 4 & E. Garcia-Fuentes 1
1Hospital Universitario Carlos Haya, Malaga, Spain; 2CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Malaga, Spain; 3Hospital San Agustín, Aviles, Spain; 4Hospital Central de Asturias, Oviedo, Spain.
Objective: Modifications in lifestyle and diet are major contributors for the high prevalence of obesity. Very few longitudinal studies have evaluated the changes in body weight over time. Dynamic changes in body weight are also an important indicator of risk for type 2 diabetes. The aim of this study is to assess factors associated with weight gain in a population of Spanish adults.
Methods: The study was undertaken in two population-based cohorts of Spain. The first phase of the ‘Asturias Study’ (1998–1999) included 1034 persons, of whom 701 were reassessed in 2004–2005. The first phase of the ‘Pizarra Study’ (1996–1998) included 1226 persons, of whom 783 were re-evaluated in 2002–2004. Both studies involved a questionnaire on socio-demographic variables and an oral glucose tolerance test (OGTT).
Results: During the follow-up, 32.3% of the participants lost weight, 34.5% gained fewer than 4 kg and 33.2% gained more than 4 kg. Weight gain was greater in persons younger than 50 years and in those with an initial body mass index below 30. Weight gain was associated with a greater incidence of diabetes and glucose dysregulation, whereas weight loss in persons with these disorders was associated with a normal OGTT 6 years later. Persons who ate watching TV, those who took less exercise and those who reported a higher daily calorie intake experienced greater weight gain.
Conclusions: The longitudinal changes in weight decisively affect the development of diabetes and glucose dysregulation. The weight is a dynamic phenomenon affected by several social customs.
Declaration of interest: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.
Funding: This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.
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Endocrine Abstracts
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