Endocrine Abstracts

Aim: In this study our aim was to investigate the relationship between obesity and vitamin D and hyperparathyroidism.

Material and Method: 127 healthy persons included in this study. Study group were divided into four groups according to body mass index (BMI). Group 1 (n=35) BMI 18.5–24.9 kg/m², Group 2 (n=35) BMI 25–29.9 kg/m², Group 3 (n=35) BMI 3.0–34.9 kg/m², Group 4 (n=22) BMI 35–40 kg/m². Anthropometric measurements were performed. Serum calcium (Ca), phosphorus (P), parathormone (PTH), 25(OH) D levels were evaluated.

Results: Negative linear relationship was found between BMI and serum Ca and Vit D (respectively, P=0.040 r=−0.181, P=0.016 r=−0.214). There was no significant relationship between BMI and PTH levels (P>0.05). A significant reduction was observed in vitamin D levels while waist circumference increases (P=0.049). There was no significant decrease in Serum Ca level (P>0.05). Significant decrease was observed in vitamin D and serum Ca while body fat mass increases (respectively, P=0.026, P=0.021). Serum Ca levels of group 2 was significantly higher than group 3 and 4 (respectively, P=0.049, P=0.000). vitamin D levels in group 4 was significantly lower than group 2 (respectively, 18.96±9.88 μg/l, 30.06±18.48 μg/l) (P>0.05). There was no significant difference in PTH levels between groups.

Conclusion: As a result of our study, we determined low vitamin D and calcium levels in obese patients.

Declaration of interest: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.

Funding: This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.