Endocrine Abstracts

Background: Different programmes are offered to help people to reduce weight. ‘The Programme of Weight Loss’ is working in the outpatient clinic in the Arkhangelsk, Russia, but its effectiveness was not assessed before.

Aim of the study was to assess the effect of the complex course ‘The Programme of Weight Loss’.

Methods: The panel study was conducted and included women participated in the two-week Programme from the 1st of January to the 31st of July 2010 with following observation during 6 months. We collected anthropometric and laboratory data, questioned them with the impact of weight on quality of life questionnaire (IWQOL-Lite) before the course and after six months. Statistical analysis was performed using Student’s paired t-test, non-parametric tests, multiple linear regression and logistic regression.

Results: We analyzed the results of 55 women. After 6 months the reduction of body mass (−11.32 kg, 95% CI: −9.24; −13.4), body mass index (−2.74 kg/m²; 95% CI: −0.69; −6.18), waist (−9.76 cm; 95% CI: −7.13; −12.39) and hip (−12.66 cm; 95% CI: −6.28; −19.04) circumferences, mass (−5.86 kg; 95% CI: −0.11; −11.84) and volume (−4.69%; 95% CI: −3.3; −6.08) of fat tissue, systolic (−12.97 mm Hg; 95% CI: −4.18; −21.76) and diastolic (−9.55 mm Hg; 95% CI: −5.68; −13.41) blood pressure, and total cholesterol (−1.1 mmol/l; 95% CI: −0.63; −1.57) were estimated. Lower basal waist circumference, shorter the length of the disease and lower basal level of total cholesterol were significantly associated with waist circumference reduction. Lower level of cholesterol also significantly predicted better decrease of body mass. Data from IWQOL-Lite indicated the significant improvement in self-assessment after six months. Initial body mass (OR=1.16; 95% CI: 1.02; 1.33), smoking habits (OR for ex-smokers=0.17; 95% CI: 0.04; 0.8); OR for current smokers=0.05; 95% CI: 0.00; 0.7) significantly influenced on possibility to refuse from the follow-ups.

Conclusions: «The Programme of Weight Loss» was effective in reduction of body mass, waist and hip circumference, blood pressure and level of total cholesterol after 6 months.

Declaration of interest: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.

Funding: This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.