ICEECE2012 Poster Presentations Female Reproduction (99 abstracts)
What is the earliest predictor of atherosclerosis in normal weight polycystic ovary syndrome; carotid intima media thickness or visceral fat ratio?
F. Besir , H. Yildirim , S. Yazgan , R. Buyukkaya , S. Kose , A. Karatas , B. Erdogmus & Y. Aydin
Duzce University Medicine School, Duzce, Turkey.
Purpose: The aim of this study in new diagnosed adult women with polycystic ovary syndrome (PCOS) was to evaluate carotid intima media thickness (CIMT) and visceral fat thickness (VFT) measurement by ultrasonography and which method can be used for atherosclerosis risk follow-up.
Methods: A case-control study was conducted on 22 PCOS women (18–30 years of age) and 22 controls. BMI was matched volunteer controls. Two different criteria were used to assess atherosclerosis risk. CIMT and VFT were measured by ultrasonography. In addition, visceral fat ratio (VFR) was calculated. The variables were compared using the χ2 test and Mann–Whitney U test.
Results: In PCOS women, impaired lipid profiles were not determined. Also, the mean CIMT and VFT were no significantly higher in PCOS subjects. But, VFR was significantly higher in PCOS women (1.21±0.33%) compared to controls (0.85±0.3%, P=0.001).
Conclusions: These findings indicate that CIMT which used early diagnosing of atherosclerosis have not increase in newly diagnosed PCOS women. In the other hand, VFR is increasing in newly diagnosed PCOS women. So, VFR can be used for diagnosis and follow-up of suspicions atherosclerosis as an early diagnostic method.
Keywords: Polycystic ovary syndrome (PCOS), atherosclerosis, carotid intima media thickness (CIMT), visceral fat thickness (VFT), visceral fat ratio (VFR).
Declaration of interest: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.
Funding: This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.
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Endocrine Abstracts
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