Endocrine Abstracts

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Over the last decade, high-resolution molecular imaging with nanoparticle has provided an unprecedented opportunity to noninvasively assess microanatomical neovascular processes associated with atherosclerosis, cancer, or arthritis as a “snap shot” or longitudinally with time. The capability to interogate biochemical markers in vivo in 3D over relatively large volumes of tissues facilitates a unique perspective of physiological and disease processes that canno...

Opportunities for applications of nanomedicine in diabetes are numerous. In type 1 diabetes, improved insulin replacement is urgently needed, but transplantation of islet cells is not routine, limited by availability of human islets and immune rejection. Longer survival of transplanted islets might be ensured by nano-encapsulation technologies which protect the islets from early cell death caused by the inflammatory in vivo environment and isolate against later immune r...