Endocrine Abstracts

Introduction: Indirect calorimetry is the most frequently used method to measure resting energy expenditure (REE), but the great expense of equipment precludes its widespread use. The best known REE calculation formula is the ‘Harris and Benedict Formula’. The aim of this study is to assess the impact of glucose metabolism status on REE.

Methods: Data from 110 subjects with impaired glucose tolerance (IGT), 108 subjects with impaired fasting glucose (IFG) and 72 control subjects with normal glucose tolerance (NGT) were analyzed. Their age, sex, weight, height, body mass index (BMI), waist–hip circumferences, glucose levels during oral gulcose tolerance test and fasting insulin levels were recorded. The degree of insulin resistance was determined with the homeostasis model assessment of insulin resistance (HOMA-IR). Fat mass values were calculated by a formula based on Quetelet index, which uses sex, weight and height measurements. For REE calculation, the Harris–Benedict equation was used.

Results: No significant differences in age, sex, BMI, fat mass, and HOMA-IR levels were determined between IGT, IFG and NGT groups. Waist circumference and waist to hip ratio of IGT group were higher than NGT group. There was no significant difference between three groups in terms of REE.

Conclusion: It is well known that diabetic patients have an increased REE than the normal population. But in this study, we concluded that impaired glucose metabolism patients who have increased risk for development of diabetes had any difference from NGT controls in terms of REE measurements.