Endocrine Abstracts

Introduction: Diabetes mellitus is equivalent of coronary artery disease (CAD), plenty of patients with CAD already has diabetes or prediabetes. Diabetes originate as result of interactions between diferent factors, like genetic and environment. The risk fatctors for type 2 diabetes are: positive family history for type 2 diabetes, obesity, age over 45 years, previous glucose intolerance or impaired fasting glucose, previous gestational diabetes or birthweight of children over 4 kg in women, hypertension (>140/90 mmHg), HDL cholesterol <0.9 mmol/l, and/or tryglicerides >2.8 mmol/l, polycystic ovary syndrome. Primary characteristics of CAD in diabetic patients are: younger age than in patients without DM, rapid progression, and diffuse and extended changes on blood vessels.

Aim: The aim of our study was to determinate presence of risk factors for cardiovascular disease in type 2 diabetes patients in Kragujevac, and the difference depending on gender.

Matherial and method: The study included all patients with type 2 diabetes patients in Kragujevac, we collected demographic data about patients, and about risk factors related to this disease.

Results: This examination registered 3108 type 2 diabetic patients, 1248 (40.1%) men and 1860 (59.9%) women. The prevalence of obesity in this population was 36.77%, in 40.4% women versus men 31.3% (P<0.001), hypertension 55.5%, women 59.7% versus men 49.2% (P<0.001), hyperlipidemia 23.5%, women 24.4% versus men 22.1% (P=0.076), smoking 10.88%, women 8.3% versus men 14.7% (P<0.001), alchocol consumers 3.76%, women 0.38% versus men 8.8%, P<0.001), birthweight of children over 4 kg in type 2 diabetic women 7.47%. Positive family hystory for diabetes was in 28.1%, women 29.2% versus men 26.4% (P=0.052), positive family hystory for CAD was in 24.3%, women 27.0% versus men 20.27% (P<0.001).

Conclusion: The prevalence of obesity and hypertension is significantly higher in women, the prevalence of smoking and alchocol consuming is higher in men with type 2 diabetes in Kragujevac.