Endocrine Abstracts

Gums inflammation (gingivitis) if not treated on time and permitted to grow, ends into periodontitis in which alveolar bone that supports teeth is invaded and destroyed. Juvenile periodontitis is a genetic disorder and can occur without plaque and calculus. It is a disease of people below 30 years of age.

Subjects and methods: This cross sectional study involved a total of 160 subjects including 80 chronic periodontitis patients and 80 healthy controls between the ages of 18–25 years. A detailed personal history, past medical and dental history was taken. Patients of chronic periodontitis were selected using community periodontal index of treatment needs (CPITN).

Blood sample were drawn and serum/plasma concentrations of LH, GH, cortisol, triidothyronine (T₃), thyroxine (T₄), TSH, ADH, parathyroid hormone (PTH), aldosterone, melatonin, calcitonin, insulin, cortisol, epinephrine, norepinephrine, estrogen, progesterone, testosterone, thymosins were measured by using standard ELISA method.

Results: The results of this study showed that serum/plasma concentrations of all the hormones were statistically significantly different in patients of Juvenile periodontitis.

The correlation between them and severity of Juvenile periodontitis was also evaluated and a highly significant positive correlation with the severity of periodontitis was found.

Conclusions: Under the influence of Juvenile periodontitis in otherwise healthy young population, the probability of being at hormonal imbalance had appreciably augmented.