Endocrine Abstracts

Transsphenoidal neurosurgery is the gold standard treatment for pituitary adenomas; however, it can be contra-indicated or ineffective. In these cases, medical treatment based on somatostatin analogs or GH receptor antagonist, can be used. Another approach is to use radiation therapy.Stereotactic radiosurgery (SR) is a procedure aiming at controlling hormone hypersecretion and tumor size of pituitary adenomas. This talk will mainly deal with the long-ter...

The transsphenoidal surgical technique has dominated ever since Jules Hardy introduced microsurgery with the use of an operation microscope in the 1960s. Since the 1990s, endoscopic techniques have alternatively been applied in transsphenoidal surgery. Both microscopy and endoscopy should be accepted as established techniques which can often be used in a complementary fashion. It must be understood that microsurgery and endoscopy differ only in that they use different optical ...

Radiotherapy of brain tumours given to children and adults is connected with various hormonal dysfunctions later in the life. There are anterior pituitary hormones deficiencies, hyperprolactinemia and precocious puberty. Their severity and frequency depends on the dose applied, age of the radiotherapy and time after radiotherapy. In children, the most important is early recognition of them, with growth hormone deficiency as most common. The impact of cranial irradiation on gon...